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Pharmacopeial Impurities (EP / USP / BP)

Amitriptyline EP Impurity B

Reference StandardAvailable on request

Order Amitriptyline EP Impurity B (CAS 6202-23-9) online at Zemixal: C20H22ClN, COA and SDS with every lot, worldwide shipping.

Pack sizes
Amitriptyline EP Impurity B chemical structure
CAS number6202-23-9
FormulaC20H22ClN
Molar mass311.8 g/mol
Physical formSolid
HS code38229090
InChIKeyVXEAYBOGHINOKW-UHFFFAOYSA-N
IUPAC nameN,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine;hydrochloride

About Amitriptyline EP Impurity B

Amitriptyline EP Impurity B belongs to the Cyclobenzaprine reference-standard family in the Zemixal catalogue. Identity at a glance (Reference Standard): CAS 6202-23-9, formula C20H22ClN and molar mass 311.8 g/mol. It is handled as a solid.

Use cases we see most often

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Safe handling

It carries the GHS signal word Danger (H301, H312, H317 and H332), so wear gloves and eye protection and work with good ventilation.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Every shipment includes a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Cyclobenzaprine

See every impurity, metabolite and related compound we list for this API.

Cyclobenzaprine standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Grade guides

Specifications and identifiers

Specifications of Amitriptyline EP Impurity B
Product nameAmitriptyline EP Impurity B
Catalogue numberZX-024074
CAS number6202-23-9
IUPAC nameN,N-dimethyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)propan-1-amine;hydrochloride
Molecular formulaC20H22ClN
Molar mass311.8 g/mol
Exact mass311.1441
GradeReference Standard
Physical formSolid
H-bond donors / acceptors1 / 1
Topological polar surface area3.2 Ų
HS code38229090
InChIKeyVXEAYBOGHINOKW-UHFFFAOYSA-N
SMILESCN(C)CCC=C1C2=CC=CC=C2C=CC3=CC=CC=C31.Cl
PubChem CID22576
SynonymsCyclobenzaprine Hydrochloride, Nortriptyline EP Impurity E Hydrochloride, Amitriptyline EP Impurity B (HCl salt), Amitriptyline Hydrochloride - Impurity B, Nortriptyline Hydrochloride - Impurity E, Amitriptyline Impurity B, Cyclobenzaprine HCL, Novo-Cycloprine, Tabradol, TNX-102, 10,11delta-Amitriptyline hydrochloride, 3-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)propyl(dimethyl)ammonium chloride

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS06 Acute toxicity
Acute toxicity
GHS07 Irritant or harmful
Irritant or harmful

Signal word Danger

  • H301Toxic if swallowed
  • H312Harmful in contact with skin
  • H317May cause an allergic skin reaction
  • H332Harmful if inhaled

Precautionary statements P261, P264, P270, P271, P272, P280, P301 + P316, P302 + P352, P304 + P340, P317, P321, P330, P333 + P317, P362 + P364, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Amitriptyline EP Impurity B
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Amitriptyline EP Impurity B

Which CAS number identifies Amitriptyline EP Impurity B?
Amitriptyline EP Impurity B is registered under CAS 6202-23-9. You may also see it listed as Cyclobenzaprine Hydrochloride, Nortriptyline EP Impurity E Hydrochloride, Amitriptyline EP Impurity B (HCl salt). Our catalogue number for this item is ZX-024074.
What are the formula and molar mass of Amitriptyline EP Impurity B?
For Amitriptyline EP Impurity B, its formula is C20H22ClN and its molar mass is 311.8 g/mol. InChIKey VXEAYBOGHINOKW-UHFFFAOYSA-N lets you match it in any structure database.
How is Amitriptyline EP Impurity B used in pharmaceutical QC?
Amitriptyline EP Impurity B is a characterised reference material linked to Cyclobenzaprine. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Amitriptyline EP Impurity B?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Amitriptyline EP Impurity B?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Amitriptyline EP Impurity B to my country?
Yes. Because Amitriptyline EP Impurity B is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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