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Pharmacopeial Impurities (EP / USP / BP)

Etoposide EP Impurity E

Reference StandardAvailable on request

Buy Etoposide EP Impurity E (CAS 6559-91-7) from Zemixal. Lab and bulk packs, batch COA, fast global delivery. Packs from 10 mg.

Pack sizes
Etoposide EP Impurity E chemical structure
CAS number6559-91-7
FormulaC21H20O8
Molar mass400.4 g/mol
Physical formSolid
HS code38229090
InChIKeyYVCVYCSAAZQOJI-JHQYFNNDSA-N
IUPAC name(5S,5aR,8aR,9R)-5-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one

About Etoposide EP Impurity E

Etoposide EP Impurity E belongs to the Etoposide reference-standard family in the Zemixal catalogue. Key data (Reference Standard): CAS 6559-91-7, formula C21H20O8 and molar mass 400.4 g/mol. It is handled as a solid.

Use cases we see most often

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Safe handling

Classified under GHS with signal word Danger and hazard statements H315, H319, H340 and H350. Read the SDS before first use.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Every shipment includes a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Etoposide

See every impurity, metabolite and related compound we list for this API.

Etoposide standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Grade guides

Specifications and identifiers

Specifications of Etoposide EP Impurity E
Product nameEtoposide EP Impurity E
Catalogue numberZX-021634
CAS number6559-91-7
IUPAC name(5S,5aR,8aR,9R)-5-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
Molecular formulaC21H20O8
Molar mass400.4 g/mol
Exact mass400.1158
GradeReference Standard
Physical formSolid
XLogP31.7
H-bond donors / acceptors2 / 8
Topological polar surface area104 Ų
HS code38229090
InChIKeyYVCVYCSAAZQOJI-JHQYFNNDSA-N
SMILESCOC1=CC(=CC(=C1O)OC)[C@H]2[C@@H]3[C@H](COC3=O)[C@@H](C4=CC5=C(C=C24)OCO5)O
PubChem CID122797
Synonyms4-Demethylepipodophyllotoxin, Etoposide - Impurity E, Podophyllotoxin - Impurity B, 4'-Demethylepipodophyllotoxin, (-)-4'-Demethylepipodophyllotoxin, 4'-O-demethylepipodophyllotoxin, 4'-demethyl epipodophyllotoxin, 4'-DMEP, 4'-demethyl-9-epipodophyllotoxin, 4-Domethylpodophyllotoxin, 4'-demethyl-epi-podophyllotoxin, etoposide aglycone, epi-4'-demethylpodophyllotoxin

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Danger

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H340May cause genetic defects
  • H350May cause cancer
  • H360May damage fertility or the unborn child

Precautionary statements P203, P264, P264 + P265, P280, P302 + P352, P305 + P351 + P338, P318, P321, P332 + P317, P337 + P317, P362 + P364, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Etoposide EP Impurity E
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Etoposide EP Impurity E

Which CAS number identifies Etoposide EP Impurity E?
Etoposide EP Impurity E is registered under CAS 6559-91-7. You may also see it listed as 4-Demethylepipodophyllotoxin, Etoposide - Impurity E, Podophyllotoxin - Impurity B. Our catalogue number for this item is ZX-021634.
What are the formula and molar mass of Etoposide EP Impurity E?
For Etoposide EP Impurity E, its formula is C21H20O8 and its molar mass is 400.4 g/mol. The systematic (IUPAC) name is (5S,5aR,8aR,9R)-5-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one. InChIKey YVCVYCSAAZQOJI-JHQYFNNDSA-N lets you match it in any structure database.
How is Etoposide EP Impurity E used in pharmaceutical QC?
Etoposide EP Impurity E is a characterised reference material linked to Etoposide. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Etoposide EP Impurity E?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Etoposide EP Impurity E?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Etoposide EP Impurity E to my country?
Yes. Because Etoposide EP Impurity E is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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