(S)-N4-(3,4-Difluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
- CAS
- 2044709-72-8
- Formula
- C18H16F2N4O2
- MW
- 358.3 g/mol
ZX-027782
API Process Intermediates & Related Compounds
trans-4-Dimethylaminocrotonic acid hydrochloride
Available on request
trans-4-Dimethylaminocrotonic acid hydrochloride (CAS 848133-35-7) supplier Zemixal: C6H12ClNO2, COA and SDS with every lot, worldwide shipping.
CAS number848133-35-7
FormulaC6H12ClNO2
Molar mass165.62 g/mol
Physical formSolid
InChIKeyUUHNQHFOIVLAQX-BJILWQEISA-N
IUPAC name(E)-4-(dimethylamino)but-2-enoic acid;hydrochloride
About trans-4-Dimethylaminocrotonic acid hydrochloride
trans-4-Dimethylaminocrotonic acid hydrochloride sits in our API Process Intermediates & Related Compounds section and ships worldwide from stock or short lead time. For your records, the material is defined by CAS 848133-35-7, formula C6H12ClNO2 and molar mass 165.62 g/mol. It is handled as a solid.
Use cases we see most often
- API route development
- Impurity fate & purge studies
- Analytical method development
- Fine chemical synthesis
Storage and safety notes
It carries the GHS signal word Warning (H319), so wear gloves and eye protection and work with good ventilation.
Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. You receive a batch certificate of analysis and a 16-section SDS with each order. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.
Reference standards for Afatinib
See every impurity, metabolite and related compound we list for this API.
Afatinib standardsTypical uses
- API route development
- Impurity fate & purge studies
- Analytical method development
- Fine chemical synthesis
Applications
Specifications and identifiers
| Product name | trans-4-Dimethylaminocrotonic acid hydrochloride |
|---|---|
| Catalogue number | ZX-034462 |
| CAS number | 848133-35-7 |
| IUPAC name | (E)-4-(dimethylamino)but-2-enoic acid;hydrochloride |
| Molecular formula | C6H12ClNO2 |
| Molar mass | 165.62 g/mol |
| Exact mass | 165.0557 |
| Physical form | Solid |
| H-bond donors / acceptors | 2 / 3 |
| Topological polar surface area | 40.5 Ų |
| InChIKey | UUHNQHFOIVLAQX-BJILWQEISA-N |
| SMILES | CN(C)C/C=C/C(=O)O.Cl |
| PubChem CID | 45358758 |
| Synonyms | 4-(Dimethylamino)-2-butenoic acid hydrochloride, (2E)-4-(dimethylamino)but-2-enoic acid hydrochloride, 2-Butenoic acid, 4-(dimethylamino)-, hydrochloride, (2E)-, (2e)-4-(dimethylamino)-2-butenoic acid hydrochloride, 2-Butenoic acid, 4-(dimethylamino)-, hydrochloride (1:1), (2E)-, (E)-4-(Dimethylamino)But-2-Enoic Acid Hydrochloride, 4-(dimethylamino)but-2-enoic acid hydrochloride, (E)-4-(Dimethylamino)but-2-enoic acid xhydrochloride, (E)-4-(dimethylamino)-2-butenoic acid hydrochloride, (E)-4-(dimethylamino) but-2-enoic acid hydrochloride, (E)-4-(Dimethylamino)-2-butenoic Acid xHydrochloride |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
Signal word Warning
- H319Causes serious eye irritation
Precautionary statements P264 + P265, P280, P305 + P351 + P338, P337 + P317
Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about trans-4-Dimethylaminocrotonic acid hydrochloride
Which CAS number identifies trans-4-Dimethylaminocrotonic acid hydrochloride?
trans-4-Dimethylaminocrotonic acid hydrochloride is registered under CAS 848133-35-7. You may also see it listed as 4-(Dimethylamino)-2-butenoic acid hydrochloride, (2E)-4-(dimethylamino)but-2-enoic acid hydrochloride, 2-Butenoic acid, 4-(dimethylamino)-, hydrochloride, (2E)-. Our catalogue number for this item is ZX-034462.
What are the formula and molar mass of trans-4-Dimethylaminocrotonic acid hydrochloride?
For trans-4-Dimethylaminocrotonic acid hydrochloride, its formula is C6H12ClNO2 and its molar mass is 165.62 g/mol. InChIKey UUHNQHFOIVLAQX-BJILWQEISA-N lets you match it in any structure database.
How is trans-4-Dimethylaminocrotonic acid hydrochloride used in pharmaceutical QC?
trans-4-Dimethylaminocrotonic acid hydrochloride is a characterised reference material linked to Afatinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for trans-4-Dimethylaminocrotonic acid hydrochloride?
The grade and assay are confirmed on the quotation and the batch COA. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with trans-4-Dimethylaminocrotonic acid hydrochloride?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship trans-4-Dimethylaminocrotonic acid hydrochloride to my country?
Yes. Because trans-4-Dimethylaminocrotonic acid hydrochloride is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.
More Afatinib standards
More in API Process Intermediates & Related Compounds
(R)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine
- CAS
- 402855-07-6
- Formula
- C18H14ClFN4O4
- MW
- 404.8 g/mol
ZX-027781
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-nitroquinazolin-4-amine
- CAS
- 179552-74-0
- Formula
- C15H10ClFN4O3
- MW
- 348.71 g/mol
ZX-027678
(S,E)-4-(Dimethylamino)-N-(4-((4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
- CAS
- 2413212-25-4
- Formula
- C24H26FN5O3
- MW
- 451.5 g/mol
ZX-027677
(S)-N4-(4-Fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
- CAS
- 2413212-07-2
- Formula
- C18H17FN4O2
- MW
- 340.4 g/mol
ZX-027676
Have a list of compounds to price?
Paste up to 200 CAS numbers into Bulk CAS lookup, or send one enquiry for everything in your quote list. We reply with price, lead time and documents.