(S,Z)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
- CAS
- 1680184-59-1
- Formula
- C24H25ClFN5O3
- MW
- 485.9 g/mol
ZX-020497
API Reference Standards
Afatinib dimaleate
Reference StandardAvailable on request
Order Afatinib dimaleate (CAS 850140-73-7) online at Zemixal: C32H33ClFN5O11, COA and SDS with every lot, worldwide shipping.
CAS number850140-73-7
FormulaC32H33ClFN5O11
Molar mass718.1 g/mol
Physical formSolid
HS code38229090
InChIKeyUSNRYVNRPYXCSP-JUGPPOIOSA-N
IUPAC namebis((Z)-but-2-enedioic acid);(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
About Afatinib dimaleate
Zemixal lists Afatinib dimaleate for laboratories that identify, quantify or control Afatinib and its related substances. Key data (Reference Standard): CAS 850140-73-7, formula C32H33ClFN5O11 and molar mass 718.1 g/mol. It is handled as a solid.
Common uses in the lab and plant
- Identification & assay
- Method development & validation
- QC reference material
Storage and safety notes
Classified under GHS with signal word Danger and hazard statements H302, H319, H361 and H362. Read the SDS before first use.
Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.
Reference standards for Afatinib
See every impurity, metabolite and related compound we list for this API.
Afatinib standardsTypical uses
- Identification & assay
- Method development & validation
- QC reference material
Applications
Specifications and identifiers
| Product name | Afatinib dimaleate |
|---|---|
| Catalogue number | ZX-020496 |
| CAS number | 850140-73-7 |
| IUPAC name | bis((Z)-but-2-enedioic acid);(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide |
| Molecular formula | C32H33ClFN5O11 |
| Molar mass | 718.1 g/mol |
| Exact mass | 717.1849 |
| Grade | Reference Standard |
| Physical form | Solid |
| H-bond donors / acceptors | 6 / 16 |
| Topological polar surface area | 238 Ų |
| HS code | 38229090 |
| InChIKey | USNRYVNRPYXCSP-JUGPPOIOSA-N |
| SMILES | CN(C/C=C/C(=O)NC1=C(C=C2N=CN=C(C2=C1)NC3=CC(=C(C=C3)F)Cl)O[C@@H]4COCC4)C.C(=C\C(=O)O)\C(=O)O.C(=C\C(=O)O)\C(=O)O |
| PubChem CID | 15606394 |
| Synonyms | Afatinib maleate, Afatinib maleate (JAN), Afatinib (BIBW2992) Dimaleate, Afatinib dimaleate (USAN), EX-A065B |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
Signal word Danger
- H302Harmful if swallowed
- H319Causes serious eye irritation
- H361Suspected of damaging fertility or the unborn child
- H362May cause harm to breast-fed children
- H372Causes damage to organs through prolonged or repeated exposure
- H373May causes damage to organs through prolonged or repeated exposure
- H410Very toxic to aquatic life with long lasting effects
Precautionary statements P203, P260, P263, P264, P264 + P265, P270, P273, P280, P301 + P317, P305 + P351 + P338, P318, P319, P330, P337 + P317, P391, P405, P501
Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about Afatinib dimaleate
Which CAS number identifies Afatinib dimaleate?
Afatinib dimaleate is registered under CAS 850140-73-7. You may also see it listed as Afatinib maleate, Afatinib maleate (JAN), Afatinib (BIBW2992) Dimaleate. Our catalogue number for this item is ZX-020496.
What are the formula and molar mass of Afatinib dimaleate?
For Afatinib dimaleate, its formula is C32H33ClFN5O11 and its molar mass is 718.1 g/mol. InChIKey USNRYVNRPYXCSP-JUGPPOIOSA-N lets you match it in any structure database.
How is Afatinib dimaleate used in pharmaceutical QC?
Afatinib dimaleate is a characterised reference material linked to Afatinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Afatinib dimaleate?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Afatinib dimaleate?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Afatinib dimaleate to my country?
Yes. Because Afatinib dimaleate is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.
More Afatinib standards
More in API Reference Standards
(S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
- CAS
- 2413212-09-4
- Formula
- C18H17ClN4O2
- MW
- 356.8 g/mol
ZX-020499
(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-hydroxybut-2-enamide
- CAS
- 2121530-37-6
- Formula
- C22H20ClFN4O4
- MW
- 458.9 g/mol
ZX-020500
(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
- CAS
- 2223677-64-1
- Formula
- C22H20ClFN4O3
- MW
- 442.9 g/mol
ZX-020501
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