(S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy) quinazoline-4,6-diamine
- CAS
- 314771-76-1
- Formula
- C18H16ClFN4O2
- MW
- 374.8 g/mol
ZX-019805
Metabolites & Degradation Products
Afatinib Impurity AFT-8
Reference StandardAvailable on request
Buy Afatinib Impurity AFT-8 (CAS 2323570-72-3) from Zemixal. Request a quote with price, lead time and documents. Catalogue no. ZX-019806.
CAS number2323570-72-3
FormulaC24H27ClFN5O4
Molar mass504 g/mol
Physical formSolid
HS code38229090
InChIKeyIQINQKMQCQYKAD-LYKKTTPLSA-N
IUPAC nameN-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-3-hydroxybutanamide
About Afatinib Impurity AFT-8
Afatinib Impurity AFT-8 is supplied by Zemixal as a characterised reference material for Afatinib analysis. Identity at a glance (Reference Standard): CAS 2323570-72-3, formula C24H27ClFN5O4 and molar mass 504 g/mol. It is handled as a solid.
Typical applications
- Metabolite identification
- Stability-indicating methods
- Impurity profiling
Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.
Reference standards for Afatinib
See every impurity, metabolite and related compound we list for this API.
Afatinib standardsTypical uses
- Metabolite identification
- Stability-indicating methods
- Impurity profiling
Applications
Specifications and identifiers
| Product name | Afatinib Impurity AFT-8 |
|---|---|
| Catalogue number | ZX-019806 |
| CAS number | 2323570-72-3 |
| IUPAC name | N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-3-hydroxybutanamide |
| Molecular formula | C24H27ClFN5O4 |
| Molar mass | 504 g/mol |
| Exact mass | 503.1736 |
| Grade | Reference Standard |
| Physical form | Solid |
| XLogP3 | 3.2 |
| H-bond donors / acceptors | 3 / 9 |
| Topological polar surface area | 109 Ų |
| HS code | 38229090 |
| InChIKey | IQINQKMQCQYKAD-LYKKTTPLSA-N |
| SMILES | CN(C)CC(CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4)O |
| PubChem CID | 163197455 |
| Synonyms | Afatinib Hydroxybutanamide Impurity, Afatinib impurity 44 |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
No GHS classification is on file for this item. Handle it as an unknown laboratory chemical and request the SDS with your quotation.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about Afatinib Impurity AFT-8
Which CAS number identifies Afatinib Impurity AFT-8?
Afatinib Impurity AFT-8 is registered under CAS 2323570-72-3. You may also see it listed as Afatinib Hydroxybutanamide Impurity, Afatinib impurity 44. Our catalogue number for this item is ZX-019806.
What are the formula and molar mass of Afatinib Impurity AFT-8?
For Afatinib Impurity AFT-8, its formula is C24H27ClFN5O4 and its molar mass is 504 g/mol. The systematic (IUPAC) name is N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)-3-hydroxybutanamide. InChIKey IQINQKMQCQYKAD-LYKKTTPLSA-N lets you match it in any structure database.
How is Afatinib Impurity AFT-8 used in pharmaceutical QC?
Afatinib Impurity AFT-8 is a characterised reference material linked to Afatinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Afatinib Impurity AFT-8?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Afatinib Impurity AFT-8?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Afatinib Impurity AFT-8 to my country?
Yes. Afatinib Impurity AFT-8 ships worldwide by express courier, air cargo or sea freight, quoted on the Incoterm you prefer, with full export documents.
More Afatinib standards
More in Metabolites & Degradation Products
1-(4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-5-hydroxypyrrolidin-2-one
- CAS
- 2223677-58-3
- Formula
- C22H20ClFN4O4
- MW
- 458.9 g/mol
ZX-019804
(S)-N-(3-Chloro-4-fluorophenyl)-6-nitro-7-(tetrahydrofuran-3-yloxy)quinazolin-4-amine
- CAS
- 314771-88-5
- Formula
- C18H14ClFN4O4
- MW
- 404.8 g/mol
ZX-019808
(S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)formamide
- CAS
- 2223677-60-7
- Formula
- C19H16ClFN4O3
- MW
- 402.8 g/mol
ZX-019809
(S,Z)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
- CAS
- 1680184-59-1
- Formula
- C24H25ClFN5O3
- MW
- 485.9 g/mol
ZX-020497
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