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Stable Isotope Labelled Standards (Deuterated, 13C, 15N)

Clozapine-d4

Reference StandardAvailable on request

Buy Clozapine-d4 (CAS 204395-52-8) from Zemixal. Lab and bulk packs, batch COA, fast global delivery. Packs from 10 mg. Catalogue no. ZX-036532.

Pack sizes
Clozapine-d4 chemical structure
CAS number204395-52-8
FormulaC18H19ClN4
Molar mass330.8 g/mol
Physical formSolid
HS code38229090
InChIKeyQZUDBNBUXVUHMW-MKQHWYKPSA-N
IUPAC name3-chloro-6-(2,2,6,6-tetradeuterio-4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine

About Clozapine-d4

Analytical teams working on Clozapine use Clozapine-d4 as a qualified comparison standard. Identity at a glance (Reference Standard): CAS 204395-52-8, formula C18H19ClN4 and molar mass 330.8 g/mol. It is handled as a solid.

Use cases we see most often

  • LC-MS/MS internal standard
  • Bioanalytical quantitation
  • Pharmacokinetic studies

Storage and safety notes

It carries the GHS signal word Danger (H301, H341 and H361), so wear gloves and eye protection and work with good ventilation.

Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Every shipment includes a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Clozapine

See every impurity, metabolite and related compound we list for this API.

Clozapine standards

Typical uses

  • LC-MS/MS internal standard
  • Bioanalytical quantitation
  • Pharmacokinetic studies

Applications

Grade guides

Specifications and identifiers

Specifications of Clozapine-d4
Product nameClozapine-d4
Catalogue numberZX-036532
CAS number204395-52-8
IUPAC name3-chloro-6-(2,2,6,6-tetradeuterio-4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine
Molecular formulaC18H19ClN4
Molar mass330.8 g/mol
Exact mass330.1549
GradeReference Standard
Physical formSolid
XLogP33.1
H-bond donors / acceptors1 / 3
Topological polar surface area30.9 Ų
HS code38229090
InChIKeyQZUDBNBUXVUHMW-MKQHWYKPSA-N
SMILES[2H]C1(CN(CC(N1C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42)([2H])[2H])C)[2H]
PubChem CID136951475
Synonyms5H-Dibenzo(b,e)(1,4)diazepine, 8-chloro-11-(4-methyl-1-piperazinyl-2,2,6,6-d4)-, 5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl-2,2,6,6-d4)-, Clozapine-d4 (4-methylpiperazinyl-2,2,6,6-d4), 8-chloro-11-(4-methylpiperazin-1-yl-2,2,6,6-d4)-5H-dibenzo[b,e][1,4]diazepine, 8-Chloro-11-[4-methyl(2,2,6,6-~2~H_4_)piperazin-1-yl]-5H-dibenzo[b,e][1,4]diazepine, 3-chloro-6-(2,2,6,6-tetradeuterio-4-methyl-piperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS06 Acute toxicity
Acute toxicity
GHS08 Health hazard
Health hazard

Signal word Danger

  • H301Toxic if swallowed
  • H341Suspected of causing genetic defects
  • H361Suspected of damaging fertility or the unborn child

Precautionary statements P203, P264, P270, P280, P301 + P316, P318, P321, P330, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Clozapine-d4
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Clozapine-d4

Which CAS number identifies Clozapine-d4?
Clozapine-d4 is registered under CAS 204395-52-8. You may also see it listed as 5H-Dibenzo(b,e)(1,4)diazepine, 8-chloro-11-(4-methyl-1-piperazinyl-2,2,6,6-d4)-, 5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl-2,2,6,6-d4)-, Clozapine-d4 (4-methylpiperazinyl-2,2,6,6-d4). Our catalogue number for this item is ZX-036532.
What are the formula and molar mass of Clozapine-d4?
For Clozapine-d4, its formula is C18H19ClN4 and its molar mass is 330.8 g/mol. The systematic (IUPAC) name is 3-chloro-6-(2,2,6,6-tetradeuterio-4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine. InChIKey QZUDBNBUXVUHMW-MKQHWYKPSA-N lets you match it in any structure database.
How is Clozapine-d4 used in pharmaceutical QC?
Clozapine-d4 is a characterised reference material linked to Clozapine. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Clozapine-d4?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Clozapine-d4?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Clozapine-d4 to my country?
Yes. Because Clozapine-d4 is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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