(3R)-N-(tert-Butoxycarbonyl)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid, 98%
- CAS
- 486460-00-8
- Formula
- C15H18F3NO4
- MW
- 333.3 g/mol
ZX-002164
API Impurities
(R)-Sitagliptin N-Boc-Acid Impurity
Reference StandardIn stock
(R)-Sitagliptin N-Boc-Acid Impurity (CAS 486460-00-8) supplier Zemixal: C15H18F3NO4, COA and SDS with every lot, worldwide shipping.
CAS number486460-00-8
FormulaC15H18F3NO4
Molar mass333.3 g/mol
Physical formSolid
HS code38229090
InChIKeyTUAXCHGULMWHIO-SECBINFHSA-N
IUPAC name(3R)-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-(2,4,5-trifluorophenyl)butanoic acid
About (R)-Sitagliptin N-Boc-Acid Impurity
(R)-Sitagliptin N-Boc-Acid Impurity belongs to the Sitagliptin reference-standard family in the Zemixal catalogue. For your records (Reference Standard), the material is defined by CAS 486460-00-8, formula C15H18F3NO4 and molar mass 333.3 g/mol. It is handled as a solid.
Use cases we see most often
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Safe handling
Hazard communication follows GHS (Warning: H302, H315, H319 and H335). Our SDS lists exposure controls and first-aid measures.
Standard pack sizes are 10 mg, 25 mg, 50 mg, 100 mg and 250 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Request pricing online and we confirm availability, documentation and freight to your country.
Reference standards for Sitagliptin
See every impurity, metabolite and related compound we list for this API.
Sitagliptin standardsTypical uses
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Applications
Specifications and identifiers
| Product name | (R)-Sitagliptin N-Boc-Acid Impurity |
|---|---|
| Catalogue number | ZX-004267 |
| CAS number | 486460-00-8 |
| IUPAC name | (3R)-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-(2,4,5-trifluorophenyl)butanoic acid |
| Molecular formula | C15H18F3NO4 |
| Molar mass | 333.3 g/mol |
| Exact mass | 333.1188 |
| Grade | Reference Standard |
| Physical form | Solid |
| XLogP3 | 2.7 |
| H-bond donors / acceptors | 2 / 7 |
| Topological polar surface area | 75.6 Ų |
| HS code | 38229090 |
| InChIKey | TUAXCHGULMWHIO-SECBINFHSA-N |
| SMILES | CC(C)(C)OC(=O)N[C@H](CC1=CC(=C(C=C1F)F)F)CC(=O)O |
| PubChem CID | 7146288 |
| Synonyms | (βR)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-2,4,5-trifluorobenzenebutanoic acid, (3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic Acid, (3R)-3-[(tert-Butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic Acid, (3R)-3-[N-(tert-Butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic Acid, (R)-3-(((tert-Butoxy)carbonyl)amino)-4-(2,4,5-trifluorophenyl)butyric Acid, (R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4,5-trifluorophenyl)butanoic Acid, (R)-N-Boc-3-Amino-4-(2,4,5-trifluorophenyl)butanoicacid, N-Boc-(R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid, Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid, (3R)-N-(tert-Butoxycarbonyl)-3-amino-4-(2,4,5-trifluorophenyl)butanoic Acid, Sitagliptin Impurity 58, (3R)-3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoic acid |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
Signal word Warning
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H411Toxic to aquatic life with long lasting effects
Precautionary statements P261, P264, P264 + P265, P270, P271, P273, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P391, P403 + P233, P405, P501
Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request | |
| 250 mg | Quoted on request | |
| 500 mg | Quoted on request | |
| 1 g | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about (R)-Sitagliptin N-Boc-Acid Impurity
Which CAS number identifies (R)-Sitagliptin N-Boc-Acid Impurity?
(R)-Sitagliptin N-Boc-Acid Impurity is registered under CAS 486460-00-8. You may also see it listed as (βR)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]-2,4,5-trifluorobenzenebutanoic acid, (3R)-3-[(1,1-Dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic Acid, (3R)-3-[(tert-Butoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic Acid. Our catalogue number for this item is ZX-004267.
What are the formula and molar mass of (R)-Sitagliptin N-Boc-Acid Impurity?
For (R)-Sitagliptin N-Boc-Acid Impurity, its formula is C15H18F3NO4 and its molar mass is 333.3 g/mol. The systematic (IUPAC) name is (3R)-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-(2,4,5-trifluorophenyl)butanoic acid. InChIKey TUAXCHGULMWHIO-SECBINFHSA-N lets you match it in any structure database.
How is (R)-Sitagliptin N-Boc-Acid Impurity used in pharmaceutical QC?
(R)-Sitagliptin N-Boc-Acid Impurity is a characterised reference material linked to Sitagliptin. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for (R)-Sitagliptin N-Boc-Acid Impurity?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with (R)-Sitagliptin N-Boc-Acid Impurity?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship (R)-Sitagliptin N-Boc-Acid Impurity to my country?
Yes. Because (R)-Sitagliptin N-Boc-Acid Impurity is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.
Other grades with CAS 486460-00-8
More Sitagliptin standards
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