Sitagliptin

Name: Sitagliptin
Brand: Zemixal
SKU: ZX-004146

IP/BP/USPAvailable on request

Order Sitagliptin (CAS 486460-32-6) online at Zemixal: C16H15F6N5O, COA and SDS with every lot, worldwide shipping. Catalogue no. ZX-004146.

Pack sizes

CAS number486460-32-6

FormulaC₁₆H₁₅F₆N₅O

Molar mass407.31 g/mol

Physical formPowder

HS code2933

Purity99%

InChIKeyMFFMDFFZMYYVKS-SECBINFHSA-N

IUPAC name(3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one

About Sitagliptin

Zemixal supplies Sitagliptin within its APIs & Bulk Drugs portfolio. For your records (IP/BP/USP), the material is defined by CAS 486460-32-6, formula C16H15F6N5O and molar mass 407.31 g/mol. Typical appearance is white crystalline powder.

Use cases we see most often

Pharmaceutical synthesis
Pharmaceutical formulation

Safe handling

Hazard communication follows GHS (Danger: H302, H318 and H373). Our SDS lists exposure controls and first-aid measures.

Standard pack sizes are 1 kg, 5 kg and 25 kg, and custom quantities are quoted on request. You receive a batch certificate of analysis and a 16-section SDS with each order. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Sitagliptin

See every impurity, metabolite and related compound we list for this API.

Sitagliptin standards

Typical uses

Pharmaceutical synthesis
Pharmaceutical formulation

Applications

Pharmaceutical Manufacturing and QC

Grade guides

IP Grade (Indian Pharmacopoeia)BP Grade (British Pharmacopoeia)USP Grade (United States Pharmacopeia)

Specifications and identifiers

Specifications of Sitagliptin
Product name	Sitagliptin
Catalogue number	ZX-004146
CAS number	486460-32-6
IUPAC name	(3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one
Molecular formula	C₁₆H₁₅F₆N₅O
Molar mass	407.31 g/mol
Exact mass	407.1181
Grade	IP/BP/USP
Purity / assay	99%
Physical form	Powder
Appearance	White crystalline powder
XLogP3	0.7
H-bond donors / acceptors	1 / 10
Topological polar surface area	77 Å²
HS code	2933
InChIKey	MFFMDFFZMYYVKS-SECBINFHSA-N
SMILES	C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=CC(=C(C=C3F)F)F)N
PubChem CID	4369359
Synonyms	sitagliptine, LEZ-763, Sitagliptin (Metformin,MK-0431), LEZ 763, Sitagliptin (13), SitagliptinMK0431, MK0431, Sitagliptin (USAN/INN), EX-A2816, WHO 8692, Sitagliptin 100 microg/mL in Acetonitrile

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

Corrosive

Irritant or harmful

Health hazard

Signal word Danger

H302Harmful if swallowed
H318Causes serious eye damage
H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements P260, P264, P264 + P265, P270, P280, P301 + P317, P305 + P354 + P338, P317, P319, P330, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Sitagliptin
1 kg	Quoted on request
5 kg	Quoted on request
25 kg	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Sitagliptin

Which CAS number identifies Sitagliptin?

Sitagliptin is registered under CAS 486460-32-6. You may also see it listed as sitagliptine, LEZ-763, Sitagliptin (Metformin,MK-0431). Our catalogue number for this item is ZX-004146.

What are the formula and molar mass of Sitagliptin?

For Sitagliptin, its formula is C16H15F6N5O and its molar mass is 407.31 g/mol. The systematic (IUPAC) name is (3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one. InChIKey MFFMDFFZMYYVKS-SECBINFHSA-N lets you match it in any structure database.

How is Sitagliptin used in pharmaceutical QC?

Sitagliptin is a characterised reference material linked to Sitagliptin. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for Sitagliptin?

This listing is IP/BP/USP grade with 99% purity. Standard packs are 1 kg, 5 kg, 25 kg. Larger quantities and custom packing can be quoted on request.

Which documents come with Sitagliptin?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship Sitagliptin to my country?

Yes. Because Sitagliptin is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

Other grades with CAS 486460-32-6

Sitagliptin WS

CAS: 486460-32-6
Formula: C₁₆H₁₅F₆N₅O
MW: 407.31 g/mol

ZX-006824

More Sitagliptin standards

More in Antidiabetic, Hormone & Metabolic APIs

(R)-Sitagliptin N-Boc-Acid Impurity

CAS: 486460-00-8
Formula: C₁₅H₁₈F₃NO₄
MW: 333.3 g/mol

ZX-004267

Sitagliptin Amide Impurity

CAS: 2137101-64-3
Formula: C₁₀H₁₁F₃N₂O
MW: 232.2 g/mol

ZX-005345

Sitagliptin Dioxo Impurity

CAS: 764667-64-3
Formula: C₁₄H₁₁F₃O₅
MW: 316.23 g/mol

ZX-005346

Sitagliptin Enamine Impurity

CAS: 767340-03-4
Formula: C₁₆H₁₃F₆N₅O
MW: 405.3 g/mol

ZX-005347

Sitagliptin FP Impurity A

CAS: 2088771-60-0
Formula: C₂₀H₁₉F₆N₅O₅
MW: 523.4 g/mol

ZX-005348

Sitagliptin FP Impurity B

CAS: 2805078-75-3
Formula: C₁₆H₁₃F₆N₅O₂
MW: 421.3 g/mol

ZX-005349

Sitagliptin FP Impurity B (R-Isomer)

CAS: 2088771-61-1
Formula: C₁₆H₁₃F₆N₅O₂
MW: 421.3 g/mol

ZX-005350

Sitagliptin FP Impurity C

CAS: 1803026-58-5
Formula: C₁₆H₁₂F₆N₄O
MW: 390.28 g/mol

ZX-005351

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