Topotecan
Topotecan (CAS 123948-87-8) supplier Zemixal. Request a quote with price, lead time and documents. Part of our Oncology APIs range.
About Topotecan
Topotecan sits in our oncology APIs section and ships worldwide from stock or short lead time. Identity at a glance (IP/BP/USP): CAS 123948-87-8, formula C23H23N3O5 and molar mass 421.4 g/mol. It is handled as a powder.
Common uses in the lab and plant
- Polymer & resin production
- Pharmaceutical formulation
Handling and storage
It carries the GHS signal word Danger (H301, H315, H319 and H335), so wear gloves and eye protection and work with good ventilation.
Available as 1 kg, 5 kg and 25 kg. Larger or split packs can be arranged. You receive a batch certificate of analysis and a 16-section SDS with each order. Request pricing online and we confirm availability, documentation and freight to your country.
Typical uses
- Polymer & resin production
- Pharmaceutical formulation
Applications
Grade guides
Specifications and identifiers
| Product name | Topotecan |
|---|---|
| Catalogue number | ZX-004221 |
| CAS number | 123948-87-8 |
| IUPAC name | (19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione |
| Molecular formula | C23H23N3O5 |
| Molar mass | 421.4 g/mol |
| Exact mass | 421.1638 |
| Grade | IP/BP/USP |
| Physical form | Powder |
| XLogP3 | 0.5 |
| H-bond donors / acceptors | 2 / 7 |
| Topological polar surface area | 103 Ų |
| HS code | 2933 |
| InChIKey | UCFGDBYHRUNTLO-QHCPKHFHSA-N |
| SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O |
| PubChem CID | 60700 |
| Synonyms | Hycamptamine, Topotecan lactone, Hycamptin, Topotecane, (S)-Topotecan, Topophore C, 9-Dimethylaminomethyl-10-hydroxycamptothecin, FF-10850 (liposomal topotecan), 9-[(dimethylamino)methyl]-10-hydroxy-(4S)-camptothecin, 9-((dimethylamino)methyl)-10-hydroxy-(4S)-camptothecin, 9 Dimethylaminomethyl 10 hydroxycamptothecin, 9-((dimethylamino)methyl)-10-hydroxy-(20S)-camptothecin |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
Signal word Danger
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H340May cause genetic defects
- H341Suspected of causing genetic defects
Precautionary statements P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501
Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.
Pack sizes
| 1 kg | Quoted on request | |
| 5 kg | Quoted on request | |
| 25 kg | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about Topotecan
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