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API Reference Standards

Trametinib

Reference StandardIn stock

Buy Trametinib (CAS 871700-17-3) from Zemixal: C26H23FIN5O4, COA and SDS with every lot, worldwide shipping. Packs from 10 mg.

Pack sizes
Trametinib chemical structure
CAS number871700-17-3
FormulaC26H23FIN5O4
Molar mass615.4 g/mol
Physical formSolid
HS code38229090
InChIKeyLIRYPHYGHXZJBZ-UHFFFAOYSA-N
IUPAC nameN-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide

About Trametinib

Trametinib is supplied by Zemixal as a characterised reference material for Trametinib analysis. Key data (Reference Standard): CAS 871700-17-3, formula C26H23FIN5O4 and molar mass 615.4 g/mol. It is handled as a solid.

Common uses in the lab and plant

  • Identification & assay
  • Method development & validation
  • QC reference material

Storage and safety notes

Hazard communication follows GHS (Danger: H317, H361, H372 and H373). Our SDS lists exposure controls and first-aid measures.

Order it in 10 mg, 25 mg, 50 mg, 100 mg and 250 mg packs or ask for a bulk quotation. You receive a certificate of analysis with characterisation data with each order. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Trametinib

See every impurity, metabolite and related compound we list for this API.

Trametinib standards

Typical uses

  • Identification & assay
  • Method development & validation
  • QC reference material

Applications

Specifications and identifiers

Specifications of Trametinib
Product nameTrametinib
Catalogue numberZX-006876
CAS number871700-17-3
IUPAC nameN-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide
Molecular formulaC26H23FIN5O4
Molar mass615.4 g/mol
Exact mass615.0779
GradeReference Standard
Physical formSolid
XLogP33.4
H-bond donors / acceptors2 / 6
Topological polar surface area102 Ų
HS code38229090
InChIKeyLIRYPHYGHXZJBZ-UHFFFAOYSA-N
SMILESCC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC=CC(=C4)NC(=O)C)C5CC5
PubChem CID11707110
SynonymsMekinist, TMT-212, MEK Inhibitor GSK1120212, Trametinib (GSK1120212), EX-A022, Trametinib (USAN), Trametinib (Standard), Trametinib (GSK1120212JTP 74057), CPD 8B

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Danger

  • H317May cause an allergic skin reaction
  • H361Suspected of damaging fertility or the unborn child
  • H372Causes damage to organs through prolonged or repeated exposure
  • H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements P203, P260, P261, P264, P270, P272, P280, P302 + P352, P318, P319, P321, P333 + P317, P362 + P364, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Trametinib
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request
250 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Trametinib

Which CAS number identifies Trametinib?
Trametinib is registered under CAS 871700-17-3. You may also see it listed as Mekinist, TMT-212, MEK Inhibitor GSK1120212. Our catalogue number for this item is ZX-006876.
What are the formula and molar mass of Trametinib?
For Trametinib, its formula is C26H23FIN5O4 and its molar mass is 615.4 g/mol. The systematic (IUPAC) name is N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide. InChIKey LIRYPHYGHXZJBZ-UHFFFAOYSA-N lets you match it in any structure database.
How is Trametinib used in pharmaceutical QC?
Trametinib is a characterised reference material linked to Trametinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Trametinib?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg, 250 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Trametinib?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Trametinib to my country?
Yes. Because Trametinib is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

More Trametinib standards

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