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API Impurities

Trametinib Impurity 11

Reference StandardIn stock

Order Trametinib Impurity 11 (CAS 871700-22-0) online at Zemixal. Request a quote with price, lead time and documents. Ships from India to 120+ countries.

Pack sizes
Trametinib Impurity 11 chemical structure
CAS number871700-22-0
FormulaC14H13FIN3O2
Molar mass401.17 g/mol
Physical formSolid
HS code38229090
InChIKeyMALTZCVPKJAUOE-UHFFFAOYSA-N
IUPAC name3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)pyrimidine-2,4-dione

About Trametinib Impurity 11

Trametinib Impurity 11 belongs to the Trametinib reference-standard family in the Zemixal catalogue. Identity at a glance (Reference Standard): CAS 871700-22-0, formula C14H13FIN3O2 and molar mass 401.17 g/mol. It is handled as a solid.

Common uses in the lab and plant

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Storage and safety notes

It carries the GHS signal word Danger (H302, H315, H319 and H335), so wear gloves and eye protection and work with good ventilation.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Trametinib

See every impurity, metabolite and related compound we list for this API.

Trametinib standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of Trametinib Impurity 11
Product nameTrametinib Impurity 11
Catalogue numberZX-005459
CAS number871700-22-0
IUPAC name3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)pyrimidine-2,4-dione
Molecular formulaC14H13FIN3O2
Molar mass401.17 g/mol
Exact mass401.0036
GradeReference Standard
Physical formSolid
XLogP32.4
H-bond donors / acceptors1 / 4
Topological polar surface area52.7 Ų
HS code38229090
InChIKeyMALTZCVPKJAUOE-UHFFFAOYSA-N
SMILESCNC1=CC(=O)N(C(=O)N1C2=C(C=C(C=C2)I)F)C3CC3
PubChem CID59717171
Synonyms3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)-2,4(1H,3H)-pyrimidinedione, 3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-methylamino-1H-pyrimidine-2,4-dione, 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)pyrimidine-2,4(1H,3H)-dione, CS-M0421, 3-cyclopropyl-1-(2-fluoro-4-iodoph, 2,4(1H,3H)-Pyrimidinedione, 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)-, 3-cyclopropyl-1-(2-fluoro-4-iodo-phenyl)-6-(methylamino)pyrimidine-2,4-dione

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful

Signal word Danger

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Trametinib Impurity 11
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Trametinib Impurity 11

Which CAS number identifies Trametinib Impurity 11?
Trametinib Impurity 11 is registered under CAS 871700-22-0. You may also see it listed as 3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)-2,4(1H,3H)-pyrimidinedione, 3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-methylamino-1H-pyrimidine-2,4-dione, 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)pyrimidine-2,4(1H,3H)-dione. Our catalogue number for this item is ZX-005459.
What are the formula and molar mass of Trametinib Impurity 11?
For Trametinib Impurity 11, its formula is C14H13FIN3O2 and its molar mass is 401.17 g/mol. The systematic (IUPAC) name is 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)pyrimidine-2,4-dione. InChIKey MALTZCVPKJAUOE-UHFFFAOYSA-N lets you match it in any structure database.
How is Trametinib Impurity 11 used in pharmaceutical QC?
Trametinib Impurity 11 is a characterised reference material linked to Trametinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Trametinib Impurity 11?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Trametinib Impurity 11?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Trametinib Impurity 11 to my country?
Yes. Because Trametinib Impurity 11 is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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