Trametinib Impurity 11
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About Trametinib Impurity 11
Trametinib Impurity 11 belongs to the Trametinib reference-standard family in the Zemixal catalogue. Identity at a glance (Reference Standard): CAS 871700-22-0, formula C14H13FIN3O2 and molar mass 401.17 g/mol. It is handled as a solid.
Common uses in the lab and plant
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Storage and safety notes
It carries the GHS signal word Danger (H302, H315, H319 and H335), so wear gloves and eye protection and work with good ventilation.
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.
See every impurity, metabolite and related compound we list for this API.
Trametinib standardsTypical uses
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Applications
Specifications and identifiers
| Product name | Trametinib Impurity 11 |
|---|---|
| Catalogue number | ZX-005459 |
| CAS number | 871700-22-0 |
| IUPAC name | 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)pyrimidine-2,4-dione |
| Molecular formula | C14H13FIN3O2 |
| Molar mass | 401.17 g/mol |
| Exact mass | 401.0036 |
| Grade | Reference Standard |
| Physical form | Solid |
| XLogP3 | 2.4 |
| H-bond donors / acceptors | 1 / 4 |
| Topological polar surface area | 52.7 Ų |
| HS code | 38229090 |
| InChIKey | MALTZCVPKJAUOE-UHFFFAOYSA-N |
| SMILES | CNC1=CC(=O)N(C(=O)N1C2=C(C=C(C=C2)I)F)C3CC3 |
| PubChem CID | 59717171 |
| Synonyms | 3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)-2,4(1H,3H)-pyrimidinedione, 3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-methylamino-1H-pyrimidine-2,4-dione, 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)pyrimidine-2,4(1H,3H)-dione, CS-M0421, 3-cyclopropyl-1-(2-fluoro-4-iodoph, 2,4(1H,3H)-Pyrimidinedione, 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-6-(methylamino)-, 3-cyclopropyl-1-(2-fluoro-4-iodo-phenyl)-6-(methylamino)pyrimidine-2,4-dione |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
Signal word Danger
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501
Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
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