(E)-N'-(1-Cyclopropyl-3-(2-fluoro-4-iodophenyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-N,N-dimethylformimidamide
- CAS
- 871700-30-0
- Formula
- C16H16FIN4O2
- MW
- 442.23 g/mol
ZX-027363
Metabolites & Degradation Products
Trametinib Dimethyl Sulfoxide
Reference StandardAvailable on request
Trametinib Dimethyl Sulfoxide (CAS 1187431-43-1) supplier Zemixal: C28H29FIN5O5S, COA and SDS with every lot, worldwide shipping.
CAS number1187431-43-1
FormulaC28H29FIN5O5S
Molar mass693.5 g/mol
Physical formSolid
HS code38229090
InChIKeyOQUFJVRYDFIQBW-UHFFFAOYSA-N
IUPAC nameN-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide;methylsulfinylmethane
About Trametinib Dimethyl Sulfoxide
Analytical teams working on Trametinib use Trametinib Dimethyl Sulfoxide as a qualified comparison standard. For your records (Reference Standard), the material is defined by CAS 1187431-43-1, formula C28H29FIN5O5S and molar mass 693.5 g/mol. It is handled as a solid.
Common uses in the lab and plant
- Metabolite identification
- Stability-indicating methods
- Impurity profiling
Handling and storage
Classified under GHS with signal word Danger and hazard statements H317, H361, H372 and H400. Read the SDS before first use.
Order it in 10 mg, 25 mg, 50 mg and 100 mg packs or ask for a bulk quotation. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.
Reference standards for Trametinib
See every impurity, metabolite and related compound we list for this API.
Trametinib standardsTypical uses
- Metabolite identification
- Stability-indicating methods
- Impurity profiling
Applications
Specifications and identifiers
| Product name | Trametinib Dimethyl Sulfoxide |
|---|---|
| Catalogue number | ZX-022939 |
| CAS number | 1187431-43-1 |
| IUPAC name | N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide;methylsulfinylmethane |
| Molecular formula | C28H29FIN5O5S |
| Molar mass | 693.5 g/mol |
| Exact mass | 693.0918 |
| Grade | Reference Standard |
| Physical form | Solid |
| H-bond donors / acceptors | 2 / 8 |
| Topological polar surface area | 138 Ų |
| HS code | 38229090 |
| InChIKey | OQUFJVRYDFIQBW-UHFFFAOYSA-N |
| SMILES | CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC=CC(=C4)NC(=O)C)C5CC5.CS(=O)C |
| PubChem CID | 50992434 |
| Synonyms | Trametinib DMSO, Trametinib DMSO solvate, Trametinib (DMSO solvate), GSK1120212 (DMSO solvate), JTP-74057 (DMSO solvate), EX-A5800, Trametinib dimethyl sulfoxide (JAN/USAN), Trametinib DMSO solvate (GSK1120212B) |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
Signal word Danger
- H317May cause an allergic skin reaction
- H361Suspected of damaging fertility or the unborn child
- H372Causes damage to organs through prolonged or repeated exposure
- H400Very toxic to aquatic life
- H410Very toxic to aquatic life with long lasting effects
Precautionary statements P203, P260, P261, P264, P270, P272, P273, P280, P302 + P352, P318, P319, P321, P333 + P317, P362 + P364, P391, P405, P501
Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about Trametinib Dimethyl Sulfoxide
Which CAS number identifies Trametinib Dimethyl Sulfoxide?
Trametinib Dimethyl Sulfoxide is registered under CAS 1187431-43-1. You may also see it listed as Trametinib DMSO, Trametinib DMSO solvate, Trametinib (DMSO solvate). Our catalogue number for this item is ZX-022939.
What are the formula and molar mass of Trametinib Dimethyl Sulfoxide?
For Trametinib Dimethyl Sulfoxide, its formula is C28H29FIN5O5S and its molar mass is 693.5 g/mol. InChIKey OQUFJVRYDFIQBW-UHFFFAOYSA-N lets you match it in any structure database.
How is Trametinib Dimethyl Sulfoxide used in pharmaceutical QC?
Trametinib Dimethyl Sulfoxide is a characterised reference material linked to Trametinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Trametinib Dimethyl Sulfoxide?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Trametinib Dimethyl Sulfoxide?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Trametinib Dimethyl Sulfoxide to my country?
Yes. Because Trametinib Dimethyl Sulfoxide is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.
More Trametinib standards
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