(Z)-3-(3-Bromo-4-fluorobenzylidene)isobenzofuran-1(3H)-one
- CAS
- 1423030-14-1
- Formula
- C15H8BrFO2
- MW
- 319.12 g/mol
ZX-011866
Impurity reference standards
Olaparib impurity standards
Zemixal lists 49 reference materials related to Olaparib, covering the drug substance itself, its process impurities and the products it forms on storage. Among them are 1 nitrosamine, 3 metabolites or hydroxylated analogues and 1 degradation product.
49reference materials
1nitrosamines
3metabolites
1degradants
Batches are supplied with a certificate of analysis, and the supporting spectra can be sent ahead of a purchase order so your QA team can review them. They are bought for system suitability, peak identification, quantitation against limits and the impurity justification sections of regulatory submissions. The nitrosamine entries support ICH M7 risk assessments and confirmatory testing at trace levels.
By impurity type
Nitrosamines1N-nitroso impurities for ICH M7 work
Metabolites3Hydroxy, desmethyl and conjugated forms
Degradants1N-oxides, dimers, lactones and breakdown products
Counts are based on product names. One compound can fall into more than one type.
All Olaparib reference materials
1–49 of 49 standards
1-(Piperazin-1-yl)butan-1-one Dihydrochloride
- CAS
- 2503206-35-5
- Formula
- C8H18Cl2N2O
- MW
- 229.14 g/mol
ZX-011906
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzonitrile
- CAS
- 1021298-68-9
- Formula
- C16H10FN3O
- MW
- 279.27 g/mol
ZX-012011
2-Methyl-1-(piperazin-1-yl)propan-1-one Hydrochloride
- CAS
- 1052542-35-4
- Formula
- C8H17ClN2O
- MW
- 192.68 g/mol
ZX-012021
4-(3-(4-(cyclopropanecarbonyl)piperazine-1-carbonyl)-2-fluorobenzyl)phthalazin-1(2H)-one
- Formula
- C24H23FN4O3
- MW
- 434.46 g/mol
ZX-012112
4-(3-(4-(Cyclopropanecarbonyl)piperazine-1-carbonyl)-4-fluorobenzoyl)phthalazin-1(2H)-one
- CAS
- 1460272-52-9
- Formula
- C24H21FN4O4
- MW
- 448.4 g/mol
ZX-030921
4-(3-Bromo-4-fluorobenzyl)phthalazin-1(2H)-one
- CAS
- 1062292-60-7
- Formula
- C15H10BrFN2O
- MW
- 333.15 g/mol
ZX-012114
4-(4-(4-(cyclopropanecarbonyl)piperazine-1-carbonyl)-3-fluorobenzyl)phthalazin-1(2H)-one
- Formula
- C24H23FN4O3
- MW
- 434.46 g/mol
ZX-012116
4-(5-(4-(cyclopropanecarbonyl)piperazine-1-carbonyl)-2-fluorobenzyl)phthalazin-1(2H)-one
- Formula
- C24H23FN4O3
- MW
- 434.5 g/mol
ZX-012121
Cyclobutyl(piperazin-1-yl)methanone Hydrochloride
- CAS
- 1428443-87-1
- Formula
- C9H17ClN2O
- MW
- 204.7 g/mol
ZX-012364
Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate
- CAS
- 61260-15-9
- Formula
- C10H11O5P
- MW
- 242.16 g/mol
ZX-012433
Tert-Butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazine-1-carboxylate
- CAS
- 763114-04-1
- Formula
- C25H27FN4O4
- MW
- 466.5 g/mol
ZX-030920
Questions
Olaparib impurities, answered
How many Olaparib impurity standards does Zemixal list?
The catalogue currently lists 49 compounds for Olaparib, including 1 nitrosamine, 3 metabolites or hydroxylated analogues and 1 degradation product. Each product page shows the CAS number where one is assigned, the structure, formula and molecular weight.
What documents come with a Olaparib impurity standard?
A certificate of analysis travels with every lot. On request we share the characterisation set, usually 1H-NMR, mass spectrum, HPLC purity and IR, and for some materials TGA or water content. Ask for the data before ordering if your QA team needs to review it.
Can Zemixal make a Olaparib impurity that is not listed?
Often yes. Send the structure, name or CAS number with the quantity you need and our sourcing team checks custom synthesis options, usually from 10 mg up to gram scale, with a quoted lead time.
Do you supply Olaparib nitrosamine impurities?
Yes. 1 N-nitroso compound is listed for Olaparib. They are used for confirmatory testing and method validation in line with ICH M7 and the nitrosamine guidance from the major regulators.