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Pharmacopeial Impurities (EP / USP / BP)

Thiamine EP Impurity E

Reference StandardAvailable on request

Buy Thiamine EP Impurity E (CAS 299-35-4) from Zemixal. Request a quote with price, lead time and documents. Packs from 10 mg.

Pack sizes
Thiamine EP Impurity E chemical structure
CAS number299-35-4
FormulaC12H16N4OS2
Molar mass296.4 g/mol
Physical formSolid
HS code38229090
InChIKeySQOCQQPFEFRKBV-UHFFFAOYSA-N
IUPAC name3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazole-2-thione

About Thiamine EP Impurity E

Thiamine EP Impurity E is supplied by Zemixal as a characterised reference material for Thiamine analysis. Identity at a glance (Reference Standard): CAS 299-35-4, formula C12H16N4OS2 and molar mass 296.4 g/mol. It is handled as a solid.

Where it is used

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Handling and storage

Hazard communication follows GHS (Warning: H319). Our SDS lists exposure controls and first-aid measures.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Thiamine

See every impurity, metabolite and related compound we list for this API.

Thiamine standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Grade guides

Specifications and identifiers

Specifications of Thiamine EP Impurity E
Product nameThiamine EP Impurity E
Catalogue numberZX-027220
CAS number299-35-4
IUPAC name3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazole-2-thione
Molecular formulaC12H16N4OS2
Molar mass296.4 g/mol
Exact mass296.0766
GradeReference Standard
Physical formSolid
XLogP30.8
H-bond donors / acceptors2 / 6
Topological polar surface area133 Ų
HS code38229090
InChIKeySQOCQQPFEFRKBV-UHFFFAOYSA-N
SMILESCC1=C(SC(=S)N1CC2=CN=C(N=C2N)C)CCO
PubChem CID67530
SynonymsThiamine Hydrochloride - Impurity E, Thiothiamine, Thioxothiamine, Thiothiamin, Thiamin Thiothiazolone, 3-(4-Amino-2-methylpyrimidin-5-ylmethyl)-5-(2-hydroxyethyl)-4-methylthiazole-2(3H)-thione, Thiamine Impurity A, 3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-thiazole-2-thione

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS07 Irritant or harmful
Irritant or harmful

Signal word Warning

  • H319Causes serious eye irritation

Precautionary statements P264 + P265, P280, P305 + P351 + P338, P337 + P317

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Thiamine EP Impurity E
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Thiamine EP Impurity E

Which CAS number identifies Thiamine EP Impurity E?
Thiamine EP Impurity E is registered under CAS 299-35-4. You may also see it listed as Thiamine Hydrochloride - Impurity E, Thiothiamine, Thioxothiamine. Our catalogue number for this item is ZX-027220.
What are the formula and molar mass of Thiamine EP Impurity E?
For Thiamine EP Impurity E, its formula is C12H16N4OS2 and its molar mass is 296.4 g/mol. The systematic (IUPAC) name is 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazole-2-thione. InChIKey SQOCQQPFEFRKBV-UHFFFAOYSA-N lets you match it in any structure database.
How is Thiamine EP Impurity E used in pharmaceutical QC?
Thiamine EP Impurity E is a characterised reference material linked to Thiamine. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Thiamine EP Impurity E?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Thiamine EP Impurity E?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Thiamine EP Impurity E to my country?
Yes. Because Thiamine EP Impurity E is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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