(R)-Methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate
- CAS
- 1234321-83-5
- Formula
- C13H14F3NO3
- MW
- 289.25 g/mol
ZX-022783
Pharmacopeial Impurities (EP / USP / BP)
Sitagliptin EP Impurity B
Reference StandardAvailable on request
Sitagliptin EP Impurity B (CAS 486460-31-5) supplier Zemixal. Lab and bulk packs, batch COA, fast global delivery. Catalogue no. ZX-022784.
CAS number486460-31-5
FormulaC16H16F5N5O
Molar mass389.32 g/mol
Physical formSolid
HS code38229090
InChIKeyABTMQWQGGARRSK-LLVKDONJSA-N
IUPAC name(3R)-3-amino-4-(2,5-difluorophenyl)-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]butan-1-one
About Sitagliptin EP Impurity B
Zemixal lists Sitagliptin EP Impurity B for laboratories that identify, quantify or control Sitagliptin and its related substances. Key data (Reference Standard): CAS 486460-31-5, formula C16H16F5N5O and molar mass 389.32 g/mol. It is handled as a solid.
Use cases we see most often
- Pharmacopeial method verification
- Impurity profiling
- QC release testing
- ANDA / DMF filings
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.
Reference standards for Sitagliptin
See every impurity, metabolite and related compound we list for this API.
Sitagliptin standardsTypical uses
- Pharmacopeial method verification
- Impurity profiling
- QC release testing
- ANDA / DMF filings
Applications
Grade guides
Specifications and identifiers
| Product name | Sitagliptin EP Impurity B |
|---|---|
| Catalogue number | ZX-022784 |
| CAS number | 486460-31-5 |
| IUPAC name | (3R)-3-amino-4-(2,5-difluorophenyl)-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]butan-1-one |
| Molecular formula | C16H16F5N5O |
| Molar mass | 389.32 g/mol |
| Exact mass | 389.1275 |
| Grade | Reference Standard |
| Physical form | Solid |
| XLogP3 | 0.6 |
| H-bond donors / acceptors | 1 / 9 |
| Topological polar surface area | 77 Ų |
| HS code | 38229090 |
| InChIKey | ABTMQWQGGARRSK-LLVKDONJSA-N |
| SMILES | C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)C[C@@H](CC3=C(C=CC(=C3)F)F)N |
| PubChem CID | 9843297 |
| Synonyms | 2,5-Difluoro Sitagliptin, Sitagliptin - Impurity B, des-F-sitagliptin, Desfluorositagliptin |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
No GHS classification is on file for this item. Handle it as an unknown laboratory chemical and request the SDS with your quotation.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about Sitagliptin EP Impurity B
Which CAS number identifies Sitagliptin EP Impurity B?
Sitagliptin EP Impurity B is registered under CAS 486460-31-5. You may also see it listed as 2,5-Difluoro Sitagliptin, Sitagliptin - Impurity B, des-F-sitagliptin. Our catalogue number for this item is ZX-022784.
What are the formula and molar mass of Sitagliptin EP Impurity B?
For Sitagliptin EP Impurity B, its formula is C16H16F5N5O and its molar mass is 389.32 g/mol. The systematic (IUPAC) name is (3R)-3-amino-4-(2,5-difluorophenyl)-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]butan-1-one. InChIKey ABTMQWQGGARRSK-LLVKDONJSA-N lets you match it in any structure database.
How is Sitagliptin EP Impurity B used in pharmaceutical QC?
Sitagliptin EP Impurity B is a characterised reference material linked to Sitagliptin. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Sitagliptin EP Impurity B?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Sitagliptin EP Impurity B?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Sitagliptin EP Impurity B to my country?
Yes. Sitagliptin EP Impurity B ships worldwide by express courier, air cargo or sea freight, quoted on the Incoterm you prefer, with full export documents.
More Sitagliptin standards
More in Pharmacopeial Impurities (EP / USP / BP)
3-Boc-amino-4-2, 4, 5-trifluorophenyl)butyric Acid
- CAS
- 1620129-74-9
- Formula
- C15H18F3NO4
- MW
- 333.3 g/mol
ZX-022785
(R)-3-((tert-Butoxycarbonyl)amino)-4-(2,4-difluorophenyl)butanoic Acid
- CAS
- 851307-12-5
- Formula
- C15H19F2NO4
- MW
- 315.31 g/mol
ZX-022782
(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one
- CAS
- 1803026-54-1
- Formula
- C16H12F6N4O
- MW
- 390.28 g/mol
ZX-022781
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