2,4-Diamino-6-(hydroxymethyl)pteridine Hydrochloride
- CAS
- 73978-41-3
- Formula
- C7H9ClN6O
- MW
- 228.64 g/mol
ZX-030535
Pharmacopeial Impurities (EP / USP / BP)
Methotrexate EP Impurity E Hydrochloride
Reference StandardAvailable on request
Buy Methotrexate EP Impurity E Hydrochloride (CAS 70844-48-3) from Zemixal. Lab and bulk packs, batch COA, fast global delivery.
CAS number70844-48-3
FormulaC30H31ClN14O4
Molar mass687.1 g/mol
Physical formSolid
HS code38229090
InChIKeyWWFYKUISNIJHNQ-UHFFFAOYSA-N
IUPAC namebis(4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoic acid);hydrochloride
About Methotrexate EP Impurity E Hydrochloride
Analytical teams working on Methotrexate use Methotrexate EP Impurity E Hydrochloride as a qualified comparison standard. For your records (Reference Standard), the material is defined by CAS 70844-48-3, formula C30H31ClN14O4 and molar mass 687.1 g/mol. It is handled as a solid.
Typical applications
- Pharmacopeial method verification
- Impurity profiling
- QC release testing
- ANDA / DMF filings
Handling and storage
Classified under GHS with signal word Warning and hazard statements H317. Read the SDS before first use.
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.
Reference standards for Methotrexate
See every impurity, metabolite and related compound we list for this API.
Methotrexate standardsTypical uses
- Pharmacopeial method verification
- Impurity profiling
- QC release testing
- ANDA / DMF filings
Applications
Grade guides
Specifications and identifiers
| Product name | Methotrexate EP Impurity E Hydrochloride |
|---|---|
| Catalogue number | ZX-030536 |
| CAS number | 70844-48-3 |
| IUPAC name | bis(4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoic acid);hydrochloride |
| Molecular formula | C30H31ClN14O4 |
| Molar mass | 687.1 g/mol |
| Exact mass | 686.2341 |
| Grade | Reference Standard |
| Physical form | Solid |
| H-bond donors / acceptors | 7 / 18 |
| Topological polar surface area | 288 Ų |
| HS code | 38229090 |
| InChIKey | WWFYKUISNIJHNQ-UHFFFAOYSA-N |
| SMILES | CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)O.CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)O.Cl |
| PubChem CID | 66957731 |
| Synonyms | Methotrexate EP Impurity E, Methotrexate - Impurity E (HCl Salt), 4-Amino-4-deoxy-N10-methylpteroic acid, hemihydrochloride, Benzoic acid, 4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)-, hydrochloride (2:1), hemihydrochloride4-amino-4-deoxy-N10-methylpteroic acid, 4-[N-(2,4-diamino-6-pteridinylmethyl)-N-methylamino]benzoic acid hemihydrochloride |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
Signal word Warning
- H317May cause an allergic skin reaction
Precautionary statements P261, P272, P280, P302 + P352, P321, P333 + P317, P362 + P364, P501
Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about Methotrexate EP Impurity E Hydrochloride
Which CAS number identifies Methotrexate EP Impurity E Hydrochloride?
Methotrexate EP Impurity E Hydrochloride is registered under CAS 70844-48-3. You may also see it listed as Methotrexate EP Impurity E, Methotrexate - Impurity E (HCl Salt), 4-Amino-4-deoxy-N10-methylpteroic acid, hemihydrochloride. Our catalogue number for this item is ZX-030536.
What are the formula and molar mass of Methotrexate EP Impurity E Hydrochloride?
For Methotrexate EP Impurity E Hydrochloride, its formula is C30H31ClN14O4 and its molar mass is 687.1 g/mol. InChIKey WWFYKUISNIJHNQ-UHFFFAOYSA-N lets you match it in any structure database.
How is Methotrexate EP Impurity E Hydrochloride used in pharmaceutical QC?
Methotrexate EP Impurity E Hydrochloride is a characterised reference material linked to Methotrexate. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Methotrexate EP Impurity E Hydrochloride?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Methotrexate EP Impurity E Hydrochloride?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Methotrexate EP Impurity E Hydrochloride to my country?
Yes. Because Methotrexate EP Impurity E Hydrochloride is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.
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