(S,Z)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
- CAS
- 1680184-59-1
- Formula
- C24H25ClFN5O3
- MW
- 485.9 g/mol
ZX-020497
API Impurities
Afatinib Nitroquinazolinol Impurity
Reference StandardAvailable on request
Afatinib Nitroquinazolinol Impurity (CAS 1449430-45-8) supplier Zemixal. Lab and bulk packs, batch COA, fast global delivery.
CAS number1449430-45-8
FormulaC14H8ClFN4O3
Molar mass334.69 g/mol
Physical formSolid
HS code38229090
InChIKeyODEICIIOTUWISY-UHFFFAOYSA-N
IUPAC name4-(3-chloro-4-fluoroanilino)-6-nitroquinazolin-7-ol
About Afatinib Nitroquinazolinol Impurity
Analytical teams working on Afatinib use Afatinib Nitroquinazolinol Impurity as a qualified comparison standard. Identity at a glance (Reference Standard): CAS 1449430-45-8, formula C14H8ClFN4O3 and molar mass 334.69 g/mol. It is handled as a solid.
Common uses in the lab and plant
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.
Reference standards for Afatinib
See every impurity, metabolite and related compound we list for this API.
Afatinib standardsTypical uses
- Analytical method development
- Method validation (AMV)
- QC release testing
- ANDA / DMF filings
Applications
Specifications and identifiers
| Product name | Afatinib Nitroquinazolinol Impurity |
|---|---|
| Catalogue number | ZX-020498 |
| CAS number | 1449430-45-8 |
| IUPAC name | 4-(3-chloro-4-fluoroanilino)-6-nitroquinazolin-7-ol |
| Molecular formula | C14H8ClFN4O3 |
| Molar mass | 334.69 g/mol |
| Exact mass | 334.0269 |
| Grade | Reference Standard |
| Physical form | Solid |
| XLogP3 | 4.2 |
| H-bond donors / acceptors | 2 / 7 |
| Topological polar surface area | 104 Ų |
| HS code | 38229090 |
| InChIKey | ODEICIIOTUWISY-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C=C1NC2=NC=NC3=CC(=C(C=C32)[N+](=O)[O-])O)Cl)F |
| PubChem CID | 137285542 |
| Synonyms | 4-((3-Chloro-4-fluorophenyl)amino)-6-nitroquinazolin-7-ol, 4-[(3-chloro-4-fluorophenyl)amino]-6-nitroquinazolin-7-ol, 7-Quinazolinol, 4-[(3-chloro-4-fluorophenyl)amino]-6-nitro-, 4-[(3-Chloro-4-fluorophenyl)amino]-6-nitro-7-quinazolinol |
Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.
Safety and GHS hazards
No GHS classification is on file for this item. Handle it as an unknown laboratory chemical and request the SDS with your quotation.
Pack sizes
| 10 mg | Quoted on request | |
| 25 mg | Quoted on request | |
| 50 mg | Quoted on request | |
| 100 mg | Quoted on request |
Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.
Questions about Afatinib Nitroquinazolinol Impurity
Which CAS number identifies Afatinib Nitroquinazolinol Impurity?
Afatinib Nitroquinazolinol Impurity is registered under CAS 1449430-45-8. You may also see it listed as 4-((3-Chloro-4-fluorophenyl)amino)-6-nitroquinazolin-7-ol, 4-[(3-chloro-4-fluorophenyl)amino]-6-nitroquinazolin-7-ol, 7-Quinazolinol, 4-[(3-chloro-4-fluorophenyl)amino]-6-nitro-. Our catalogue number for this item is ZX-020498.
What are the formula and molar mass of Afatinib Nitroquinazolinol Impurity?
For Afatinib Nitroquinazolinol Impurity, its formula is C14H8ClFN4O3 and its molar mass is 334.69 g/mol. The systematic (IUPAC) name is 4-(3-chloro-4-fluoroanilino)-6-nitroquinazolin-7-ol. InChIKey ODEICIIOTUWISY-UHFFFAOYSA-N lets you match it in any structure database.
How is Afatinib Nitroquinazolinol Impurity used in pharmaceutical QC?
Afatinib Nitroquinazolinol Impurity is a characterised reference material linked to Afatinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Afatinib Nitroquinazolinol Impurity?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Afatinib Nitroquinazolinol Impurity?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Afatinib Nitroquinazolinol Impurity to my country?
Yes. Afatinib Nitroquinazolinol Impurity ships worldwide by express courier, air cargo or sea freight, quoted on the Incoterm you prefer, with full export documents.
More Afatinib standards
More in API Impurities
(S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
- CAS
- 2413212-09-4
- Formula
- C18H17ClN4O2
- MW
- 356.8 g/mol
ZX-020499
(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-hydroxybut-2-enamide
- CAS
- 2121530-37-6
- Formula
- C22H20ClFN4O4
- MW
- 458.9 g/mol
ZX-020500
(S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide
- CAS
- 2223677-64-1
- Formula
- C22H20ClFN4O3
- MW
- 442.9 g/mol
ZX-020501
Have a list of compounds to price?
Paste up to 200 CAS numbers into Bulk CAS lookup, or send one enquiry for everything in your quote list. We reply with price, lead time and documents.