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Metabolites & Degradation Products

Afatinib Hydroxy impurity

Reference StandardAvailable on request

Order Afatinib Hydroxy impurity (CAS 2223677-61-8) online at Zemixal. Lab and bulk packs, batch COA, fast global delivery.

Pack sizes
Afatinib Hydroxy impurity chemical structure
CAS number2223677-61-8
FormulaC20H19ClFN5O2
Molar mass415.8 g/mol
Physical formSolid
HS code38229090
InChIKeyVOPXRQCNCZEDLI-ONEGZZNKSA-N
IUPAC name(E)-N-[4-(3-chloro-4-fluoroanilino)-7-hydroxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide

About Afatinib Hydroxy impurity

Zemixal lists Afatinib Hydroxy impurity for laboratories that identify, quantify or control Afatinib and its related substances. Key data (Reference Standard): CAS 2223677-61-8, formula C20H19ClFN5O2 and molar mass 415.8 g/mol. It is handled as a solid.

Typical applications

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Each lot travels with a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Afatinib

See every impurity, metabolite and related compound we list for this API.

Afatinib standards

Typical uses

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling

Applications

Specifications and identifiers

Specifications of Afatinib Hydroxy impurity
Product nameAfatinib Hydroxy impurity
Catalogue numberZX-019807
CAS number2223677-61-8
IUPAC name(E)-N-[4-(3-chloro-4-fluoroanilino)-7-hydroxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Molecular formulaC20H19ClFN5O2
Molar mass415.8 g/mol
Exact mass415.1211
GradeReference Standard
Physical formSolid
XLogP33.3
H-bond donors / acceptors3 / 7
Topological polar surface area90.4 Ų
HS code38229090
InChIKeyVOPXRQCNCZEDLI-ONEGZZNKSA-N
SMILESCN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O
PubChem CID136478438
SynonymsAfatinib Hydroxyquinazolin Impurity, Afatinib impurity V

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

No GHS classification is on file for this item. Handle it as an unknown laboratory chemical and request the SDS with your quotation.

Pack sizes

Pack sizes of Afatinib Hydroxy impurity
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Afatinib Hydroxy impurity

Which CAS number identifies Afatinib Hydroxy impurity?
Afatinib Hydroxy impurity is registered under CAS 2223677-61-8. You may also see it listed as Afatinib Hydroxyquinazolin Impurity, Afatinib impurity V. Our catalogue number for this item is ZX-019807.
What are the formula and molar mass of Afatinib Hydroxy impurity?
For Afatinib Hydroxy impurity, its formula is C20H19ClFN5O2 and its molar mass is 415.8 g/mol. The systematic (IUPAC) name is (E)-N-[4-(3-chloro-4-fluoroanilino)-7-hydroxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide. InChIKey VOPXRQCNCZEDLI-ONEGZZNKSA-N lets you match it in any structure database.
How is Afatinib Hydroxy impurity used in pharmaceutical QC?
Afatinib Hydroxy impurity is a characterised reference material linked to Afatinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Afatinib Hydroxy impurity?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Afatinib Hydroxy impurity?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Afatinib Hydroxy impurity to my country?
Yes. Afatinib Hydroxy impurity ships worldwide by express courier, air cargo or sea freight, quoted on the Incoterm you prefer, with full export documents.

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