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API Impurities

(S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine

Reference StandardAvailable on request

Order (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine (CAS 2413212-09-4) online at Zemixal…

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(S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine chemical structure
CAS number2413212-09-4
FormulaC18H17ClN4O2
Molar mass356.8 g/mol
Physical formSolid
HS code38229090
InChIKeyVGCTYFLBQMFZEW-ZDUSSCGKSA-N
IUPAC name4-N-(3-chlorophenyl)-7-[(3S)-oxolan-3-yl]oxyquinazoline-4,6-diamine

About (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine

Zemixal lists (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine for laboratories that identify, quantify or control Afatinib and its related substances. Identity at a glance (Reference Standard): CAS 2413212-09-4, formula C18H17ClN4O2 and molar mass 356.8 g/mol. It is handled as a solid.

Use cases we see most often

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Every shipment includes a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Afatinib

See every impurity, metabolite and related compound we list for this API.

Afatinib standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Specifications and identifiers

Specifications of (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
Product name(S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
Catalogue numberZX-020499
CAS number2413212-09-4
IUPAC name4-N-(3-chlorophenyl)-7-[(3S)-oxolan-3-yl]oxyquinazoline-4,6-diamine
Molecular formulaC18H17ClN4O2
Molar mass356.8 g/mol
Exact mass356.104
GradeReference Standard
Physical formSolid
XLogP33.4
H-bond donors / acceptors2 / 6
Topological polar surface area82.3 Ų
HS code38229090
InChIKeyVGCTYFLBQMFZEW-ZDUSSCGKSA-N
SMILESC1COC[C@H]1OC2=C(C=C3C(=C2)N=CN=C3NC4=CC(=CC=C4)Cl)N
PubChem CID125272208
SynonymsDesfluoro-N-des(4-dimethylamino-2-en-1-oxo)butyl Afatinib

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

No GHS classification is on file for this item. Handle it as an unknown laboratory chemical and request the SDS with your quotation.

Pack sizes

Pack sizes of (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine

Which CAS number identifies (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine?
(S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine is registered under CAS 2413212-09-4. You may also see it listed as Desfluoro-N-des(4-dimethylamino-2-en-1-oxo)butyl Afatinib. Our catalogue number for this item is ZX-020499.
What are the formula and molar mass of (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine?
For (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine, its formula is C18H17ClN4O2 and its molar mass is 356.8 g/mol. The systematic (IUPAC) name is 4-N-(3-chlorophenyl)-7-[(3S)-oxolan-3-yl]oxyquinazoline-4,6-diamine. InChIKey VGCTYFLBQMFZEW-ZDUSSCGKSA-N lets you match it in any structure database.
How is (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine used in pharmaceutical QC?
(S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine is a characterised reference material linked to Afatinib. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine to my country?
Yes. (S)-N4-(3-chlorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine ships worldwide by express courier, air cargo or sea freight, quoted on the Incoterm you prefer, with full export documents.

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