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API Impurities

5-Formyl-5,6,7,8-tetrahydropteroic acid

Reference StandardAvailable on request

5-Formyl-5,6,7,8-tetrahydropteroic acid (CAS 4349-43-3) supplier Zemixal. Lab and bulk packs, batch COA, fast global delivery.

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5-Formyl-5,6,7,8-tetrahydropteroic acid chemical structure
CAS number4349-43-3
FormulaC15H16N6O4
Molar mass344.33 g/mol
Physical formSolid
HS code38229090
InChIKeyCQQLECJFFZOOBZ-UHFFFAOYSA-N
IUPAC name4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoic acid

About 5-Formyl-5,6,7,8-tetrahydropteroic acid

5-Formyl-5,6,7,8-tetrahydropteroic acid is supplied by Zemixal as a characterised reference material for Folinic Acid analysis. Key data (Reference Standard): CAS 4349-43-3, formula C15H16N6O4 and molar mass 344.33 g/mol. It is handled as a solid.

Where it is used

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Safe handling

Classified under GHS with signal word Danger and hazard statements H317 and H334. Read the SDS before first use.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Folinic Acid

See every impurity, metabolite and related compound we list for this API.

Folinic Acid standards

Typical uses

  • Analytical method development
  • Method validation (AMV)
  • QC release testing
  • ANDA / DMF filings

Applications

Specifications and identifiers

Specifications of 5-Formyl-5,6,7,8-tetrahydropteroic acid
Product name5-Formyl-5,6,7,8-tetrahydropteroic acid
Catalogue numberZX-023088
CAS number4349-43-3
IUPAC name4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoic acid
Molecular formulaC15H16N6O4
Molar mass344.33 g/mol
Exact mass344.1233
GradeReference Standard
Physical formSolid
XLogP3-0.5
H-bond donors / acceptors5 / 7
Topological polar surface area149 Ų
HS code38229090
InChIKeyCQQLECJFFZOOBZ-UHFFFAOYSA-N
SMILESC1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)O
PubChem CID135991838
Synonyms5-Formyltetrahydropteroic Acid, 5-formyl-4HPA, 4-(((2-Amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoic acid, 4-(((2-Amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoic acid, 4-[[(2-Amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid, (6S)-5-Formyl-5,6,7,8-tetrahydropteroic Acid, 4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoic acid

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS08 Health hazard
Health hazard

Signal word Danger

  • H317May cause an allergic skin reaction
  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements P233, P260, P261, P271, P272, P280, P284, P302 + P352, P304 + P340, P321, P333 + P317, P342 + P316, P362 + P364, P403, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of 5-Formyl-5,6,7,8-tetrahydropteroic acid
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about 5-Formyl-5,6,7,8-tetrahydropteroic acid

Which CAS number identifies 5-Formyl-5,6,7,8-tetrahydropteroic acid?
5-Formyl-5,6,7,8-tetrahydropteroic acid is registered under CAS 4349-43-3. You may also see it listed as 5-Formyltetrahydropteroic Acid, 5-formyl-4HPA, 4-(((2-Amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoic acid. Our catalogue number for this item is ZX-023088.
What are the formula and molar mass of 5-Formyl-5,6,7,8-tetrahydropteroic acid?
For 5-Formyl-5,6,7,8-tetrahydropteroic acid, its formula is C15H16N6O4 and its molar mass is 344.33 g/mol. The systematic (IUPAC) name is 4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoic acid. InChIKey CQQLECJFFZOOBZ-UHFFFAOYSA-N lets you match it in any structure database.
How is 5-Formyl-5,6,7,8-tetrahydropteroic acid used in pharmaceutical QC?
5-Formyl-5,6,7,8-tetrahydropteroic acid is a characterised reference material linked to Folinic Acid. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for 5-Formyl-5,6,7,8-tetrahydropteroic acid?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with 5-Formyl-5,6,7,8-tetrahydropteroic acid?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship 5-Formyl-5,6,7,8-tetrahydropteroic acid to my country?
Yes. Because 5-Formyl-5,6,7,8-tetrahydropteroic acid is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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