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API Reference Standards

Methotrexate Disodium Salt

Reference StandardIn stock

Order Methotrexate Disodium Salt (CAS 7413-34-5) online at Zemixal. Lab and bulk packs, batch COA, fast global delivery.

Pack sizes
Methotrexate Disodium Salt chemical structure
CAS number7413-34-5
FormulaC20H20N8Na2O5
Molar mass498.4 g/mol
Physical formSolid
HS code38229090
InChIKeyDASQOOZCTWOQPA-GXKRWWSZSA-L
IUPAC namedisodium;(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioate

About Methotrexate Disodium Salt

Methotrexate Disodium Salt is supplied by Zemixal as a characterised reference material for Methotrexate analysis. Key data (Reference Standard): CAS 7413-34-5, formula C20H20N8Na2O5 and molar mass 498.4 g/mol. It is handled as a solid.

Common uses in the lab and plant

  • Identification & assay
  • Method development & validation
  • QC reference material

Storage and safety notes

It carries the GHS signal word Danger (H301, H311, H315 and H319), so wear gloves and eye protection and work with good ventilation.

Order it in 10 mg, 25 mg, 50 mg, 100 mg and 250 mg packs or ask for a bulk quotation. Each lot travels with a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Methotrexate

See every impurity, metabolite and related compound we list for this API.

Methotrexate standards

Typical uses

  • Identification & assay
  • Method development & validation
  • QC reference material

Applications

Specifications and identifiers

Specifications of Methotrexate Disodium Salt
Product nameMethotrexate Disodium Salt
Catalogue numberZX-006647
CAS number7413-34-5
IUPAC namedisodium;(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioate
Molecular formulaC20H20N8Na2O5
Molar mass498.4 g/mol
Exact mass498.1352
GradeReference Standard
Physical formSolid
H-bond donors / acceptors3 / 12
Topological polar surface area216 Ų
HS code38229090
InChIKeyDASQOOZCTWOQPA-GXKRWWSZSA-L
SMILESCN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]
PubChem CID11329481
SynonymsAmethopterin sodium, Methotrexate Lederle, Metoart, Metotrexato Lederle, Sodium methotrexate, N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic Acid Disodium Salt, Disodium methotrexate, Abitrexate, Methotrexate Lpf, Folex Pfs, Mexate-Aq Preserved, Mexate-Aq

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS06 Acute toxicity
Acute toxicity
GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Danger

  • H301Toxic if swallowed
  • H311Toxic in contact with skin
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H331Toxic if inhaled
  • H335May cause respiratory irritation
  • H340May cause genetic defects
  • H360May damage fertility or the unborn child

Precautionary statements P203, P261, P262, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P316, P318, P319, P321, P330, P332 + P317, P337 + P317, P361 + P364, P362 + P364, P403 + P233, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Methotrexate Disodium Salt
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request
250 mgQuoted on request
500 mgQuoted on request
1 gQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Methotrexate Disodium Salt

Which CAS number identifies Methotrexate Disodium Salt?
Methotrexate Disodium Salt is registered under CAS 7413-34-5. You may also see it listed as Amethopterin sodium, Methotrexate Lederle, Metoart. Our catalogue number for this item is ZX-006647.
What are the formula and molar mass of Methotrexate Disodium Salt?
For Methotrexate Disodium Salt, its formula is C20H20N8Na2O5 and its molar mass is 498.4 g/mol. InChIKey DASQOOZCTWOQPA-GXKRWWSZSA-L lets you match it in any structure database.
How is Methotrexate Disodium Salt used in pharmaceutical QC?
Methotrexate Disodium Salt is a characterised reference material linked to Methotrexate. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Methotrexate Disodium Salt?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Methotrexate Disodium Salt?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Methotrexate Disodium Salt to my country?
Yes. Because Methotrexate Disodium Salt is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

Other grades with CAS 7413-34-5

More Methotrexate standards

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