Methotrexate Impurity (Stage-3)

Name: Methotrexate Impurity (Stage-3)
Brand: Zemixal
SKU: ZX-004947

Reference StandardIn stock

Methotrexate Impurity (Stage-3) (CAS 2378-95-2) supplier Zemixal. Request a quote with price, lead time and documents. Packs from 10 mg.

Pack sizes

Methotrexate Impurity (Stage-3) chemical structure

CAS number2378-95-2

FormulaC₁₇H₂₄N₂O₅

Molar mass336.4 g/mol

Physical formSolid

HS code38229090

InChIKeyWBYNXAAEBPJETG-AWEZNQCLSA-N

IUPAC namediethyl (2S)-2-[[4-(methylamino)benzoyl]amino]pentanedioate

About Methotrexate Impurity (Stage-3)

Analytical teams working on Methotrexate use Methotrexate Impurity (Stage-3) as a qualified comparison standard. Identity at a glance (Reference Standard): CAS 2378-95-2, formula C17H24N2O5 and molar mass 336.4 g/mol. It is handled as a solid.

Where it is used

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Safe handling

It carries the GHS signal word Warning (H302+H312+H332, H302, H312 and H332), so wear gloves and eye protection and work with good ventilation.

Order it in 10 mg, 25 mg, 50 mg, 100 mg and 250 mg packs or ask for a bulk quotation. Every shipment includes a certificate of analysis with characterisation data. Request pricing online and we confirm availability, documentation and freight to your country.

Reference standards for Methotrexate

See every impurity, metabolite and related compound we list for this API.

Methotrexate standards

Typical uses

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QC Research Labs and Universities

Specifications and identifiers

Specifications of Methotrexate Impurity (Stage-3)
Product name	Methotrexate Impurity (Stage-3)
Catalogue number	ZX-004947
CAS number	2378-95-2
IUPAC name	diethyl (2S)-2-[[4-(methylamino)benzoyl]amino]pentanedioate
Molecular formula	C₁₇H₂₄N₂O₅
Molar mass	336.4 g/mol
Exact mass	336.1685
Grade	Reference Standard
Physical form	Solid
XLogP3	2.1
H-bond donors / acceptors	2 / 6
Topological polar surface area	93.7 Å²
HS code	38229090
InChIKey	WBYNXAAEBPJETG-AWEZNQCLSA-N
SMILES	CCOC(=O)CC[C@@H](C(=O)OCC)NC(=O)C1=CC=C(C=C1)NC
PubChem CID	75413
Synonyms	N-(4-N-Methylaminobenzoyl)-L-glutamic acid diethyl ester, 1,5-Diethyl N-[4-(methylamino)benzoyl]-L-glutamate, (S)-Diethyl 2-(4-(methylamino)benzamido)pentanedioate, Diethyl N-(p-N-methylaminobenzoyl)glutamate, Diethyl N-[4-(methylamino)benzoyl]-L-glutamate, Diethyl N-(4-(methylamino)benzoyl)-L-glutamate, N-(p-Methylaminobenzoyl)glutamic acid diethyl ester, L-Glutamic acid, N-(4-(methylamino)benzoyl)-, diethyl ester, Glutamic acid, N-(p-(methylamino)benzoyl)-, diethyl ester, L-, L-Glutamic acid, N-(4-(methylamino)benzoyl)-, 1,5-diethyl ester, L-Glutamic acid, N-[4-(methylamino)benzoyl]-, 1,5-diethyl ester, L-Glutamic acid, N-[4-(methylamino)benzoyl]-, diethyl ester

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

Irritant or harmful

Health hazard

Signal word Warning

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H341Suspected of causing genetic defects
H361Suspected of damaging fertility or the unborn child

Precautionary statements P203, P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P318, P321, P330, P362 + P364, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Methotrexate Impurity (Stage-3)
10 mg	Quoted on request
25 mg	Quoted on request
50 mg	Quoted on request
100 mg	Quoted on request
250 mg	Quoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Methotrexate Impurity (Stage-3)

Which CAS number identifies Methotrexate Impurity (Stage-3)?

Methotrexate Impurity (Stage-3) is registered under CAS 2378-95-2. You may also see it listed as N-(4-N-Methylaminobenzoyl)-L-glutamic acid diethyl ester, 1,5-Diethyl N-[4-(methylamino)benzoyl]-L-glutamate, (S)-Diethyl 2-(4-(methylamino)benzamido)pentanedioate. Our catalogue number for this item is ZX-004947.

What are the formula and molar mass of Methotrexate Impurity (Stage-3)?

For Methotrexate Impurity (Stage-3), its formula is C17H24N2O5 and its molar mass is 336.4 g/mol. The systematic (IUPAC) name is diethyl (2S)-2-[[4-(methylamino)benzoyl]amino]pentanedioate. InChIKey WBYNXAAEBPJETG-AWEZNQCLSA-N lets you match it in any structure database.

How is Methotrexate Impurity (Stage-3) used in pharmaceutical QC?

Methotrexate Impurity (Stage-3) is a characterised reference material linked to Methotrexate. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.

What grade and pack sizes are available for Methotrexate Impurity (Stage-3)?

This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg, 250 mg. Larger quantities and custom packing can be quoted on request.

Which documents come with Methotrexate Impurity (Stage-3)?

Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.

Can Zemixal ship Methotrexate Impurity (Stage-3) to my country?

Yes. Because Methotrexate Impurity (Stage-3) is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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