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Pharmacopeial Impurities (EP / USP / BP)

Methotrexate EP Impurity J

Reference StandardAvailable on request

Methotrexate EP Impurity J (CAS 34378-65-9) supplier Zemixal. Request a quote with price, lead time and documents. Catalogue no. ZX-020332.

Pack sizes
Methotrexate EP Impurity J chemical structure
CAS number34378-65-9
FormulaC22H26N8O5
Molar mass482.5 g/mol
Physical formSolid
HS code38229090
InChIKeyDIQFVFAFHNQUTG-HNNXBMFYSA-N
IUPAC namedimethyl (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioate

About Methotrexate EP Impurity J

Zemixal lists Methotrexate EP Impurity J for laboratories that identify, quantify or control Methotrexate and its related substances. Identity at a glance (Reference Standard): CAS 34378-65-9, formula C22H26N8O5 and molar mass 482.5 g/mol. It is handled as a solid.

Typical applications

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. You receive a certificate of analysis with characterisation data with each order. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Methotrexate

See every impurity, metabolite and related compound we list for this API.

Methotrexate standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Grade guides

Specifications and identifiers

Specifications of Methotrexate EP Impurity J
Product nameMethotrexate EP Impurity J
Catalogue numberZX-020332
CAS number34378-65-9
IUPAC namedimethyl (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioate
Molecular formulaC22H26N8O5
Molar mass482.5 g/mol
Exact mass482.2026
GradeReference Standard
Physical formSolid
XLogP30.2
H-bond donors / acceptors3 / 12
Topological polar surface area189 Ų
HS code38229090
InChIKeyDIQFVFAFHNQUTG-HNNXBMFYSA-N
SMILESCN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)OC)C(=O)OC
PubChem CID118159
SynonymsMethotrexate Dimethylester Hydrochloride, Methotrexate - Impurity J, Methotrexate Dimethyl Ester, Dimethyl methotrexate, (S)-Dimethyl 2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioate

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

No GHS classification is on file for this item. Handle it as an unknown laboratory chemical and request the SDS with your quotation.

Pack sizes

Pack sizes of Methotrexate EP Impurity J
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Methotrexate EP Impurity J

Which CAS number identifies Methotrexate EP Impurity J?
Methotrexate EP Impurity J is registered under CAS 34378-65-9. You may also see it listed as Methotrexate Dimethylester Hydrochloride, Methotrexate - Impurity J, Methotrexate Dimethyl Ester. Our catalogue number for this item is ZX-020332.
What are the formula and molar mass of Methotrexate EP Impurity J?
For Methotrexate EP Impurity J, its formula is C22H26N8O5 and its molar mass is 482.5 g/mol. The systematic (IUPAC) name is dimethyl (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioate. InChIKey DIQFVFAFHNQUTG-HNNXBMFYSA-N lets you match it in any structure database.
How is Methotrexate EP Impurity J used in pharmaceutical QC?
Methotrexate EP Impurity J is a characterised reference material linked to Methotrexate. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Methotrexate EP Impurity J?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Methotrexate EP Impurity J?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Methotrexate EP Impurity J to my country?
Yes. Methotrexate EP Impurity J ships worldwide by express courier, air cargo or sea freight, quoted on the Incoterm you prefer, with full export documents.

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