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APIs

CNS & Psychiatric APIs

Antidepressant, antipsychotic, antiparkinsonian, anxiolytic and local anaesthetic APIs for generic development and commercial formulation.
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CNS medicines cover a wide range of chemistry, from tricyclic antidepressants to modern atypical antipsychotics. This sub-category supplies drug substances for psychiatric, neurological and anaesthetic products. Examples are Aripiprazole, Amisulpride, Agomelatine, Amitriptyline HCl, Buspirone HCl, Biperiden HCl, Benzhexol and the local anaesthetic Benzocaine.

Several CNS molecules show polymorphism that affects solubility and stability. Aripiprazole, for instance, exists in multiple anhydrous and hydrate forms. Buyers should state the required form along with assay, related substances and residual solvent limits. Some molecules in this therapy area are controlled substances in certain countries and require permits for both export and import, which we confirm before quoting.

APIs are packed in sealed, light-resistant containers and shipped with the manufacturer's COA and an SDS. Development samples and commercial lots are both possible for many molecules. Share your target market and intended dosage form so we can match a manufacturer with suitable documentation.

CNS & Psychiatric APIs: questions buyers ask

Why does polymorphic form matter for aripiprazole?
Aripiprazole can crystallise in several forms that differ in solubility, hygroscopicity and stability. A form change during storage or processing can alter dissolution and bioequivalence. Generic developers therefore specify the polymorph that matches the reference product and check it by XRPD on incoming lots.
Are any CNS APIs controlled for export?
Some psychotropic substances are scheduled under international conventions or national law and need export and import authorisations. Most antidepressants and antipsychotics are not controlled, but certain anxiolytics and sedatives are. We confirm the status of each molecule for India and your country when quoting.
Can benzocaine be supplied for non-pharmaceutical uses?
Benzocaine is used in pharmaceutical, veterinary and some cosmetic products. We supply it with pharmacopoeial grade documentation where the grade exists. Tell us the end use and destination so we can match the right grade and confirm any import requirements that apply to your application.

Have a list of compounds to price?

Paste up to 200 CAS numbers into Bulk CAS lookup, or send one enquiry for everything in your quote list. We reply with price, lead time and documents.

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