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APIs

Respiratory & Antiallergic APIs

Bronchodilator, mucolytic, antihistamine and inhaled corticosteroid APIs for respiratory and allergy products, supplied to pharmacopoeial grades.
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Respiratory and allergy products range from cough syrups to dry powder inhalers, and the APIs behind them vary just as much. This sub-category lists mucolytics such as Ambroxol HCl, Bromhexine and Acebrophylline, bronchodilators including Aminophylline and Bambuterol, antihistamines such as Cetirizine and Buclizine, and the inhaled corticosteroid Budesonide.

Specifications depend heavily on the dosage form. Inhaled drugs like budesonide need tight particle size control in the respirable range. Syrups and oral solutions call for good solubility and taste-related impurity control, while tablets focus on flow and compression. Tell us which dosage form you are making so we can match a manufacturer whose grade fits.

Each lot ships with the manufacturer's COA and an SDS in sealed packaging that protects against moisture. Samples for formulation trials can often be arranged. Use the quote panel to group several respiratory APIs in one enquiry if you are planning a combination product.

Respiratory & Antiallergic APIs: questions buyers ask

What particle size is needed for inhaled budesonide?
For dry powder and metered-dose inhalers, most particles must fall below about 5 µm so they reach the lower airways. Suppliers micronise the API and report a particle size distribution on the COA. Your device and formulation will set the exact limits, which should be agreed with the manufacturer.
Is cetirizine supplied as the free base or a salt?
Cetirizine is normally supplied as the dihydrochloride, which is the form used in most tablets and syrups and the one described in the main pharmacopoeias. Its levorotatory enantiomer, levocetirizine, is a separate API. State the exact form you need so the quote and COA match your product.
Can respiratory APIs be supplied for veterinary products?
Several molecules, such as bromhexine and aminophylline, are used in veterinary medicine as well. We can quote these for veterinary formulators with the appropriate grade and documents. Mention the end use and the destination so we can check import rules that apply to veterinary active substances.

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