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Lab Reagents

Synthetic, Protecting & Derivatization Reagents

Coupling agents, strong bases, protecting group reagents, Wittig salts, derivatisation agents and solid-supported reagents for organic synthesis and analysis.
342 productsCOA + SDS with every lot
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GridList
2-Ethylhexene
CAS
1632-16-2
Formula
C8H16
MW
112.21 g/mol
ZX-045658

This sub-category gathers the reagents that make bonds, protect groups or tag molecules for analysis. It includes amidine bases such as 1,8-Diazabicycloundecene (DBU) and 1,4-Diazabicyclo[2.2.2]octane (DABCO), Wittig salts like (Methoxymethyl)triphenylphosphonium chloride, acetal-forming agents such as 2,2'-Dimethoxypropane, cyclodextrin hosts and polymer-supported reagents including aminomethyl polystyrene resin.

Chemists generally buy these on the strength of reactivity and dryness. Bases and phosphonium salts absorb moisture, which quietly lowers yields, so check water content and storage advice. Derivatisation reagents used before GC or HPLC need low background peaks, and resin loading in mmol/g decides how much reagent is needed per reaction.

Packs run from a few grams for route scouting to kilograms for pilot work, sealed under inert gas where the reagent requires it. Each lot ships with a COA and SDS. If you are planning a multi-step synthesis, add all reagents to the quote panel and send them as one enquiry.

Synthetic, Protecting & Derivatization Reagents: questions buyers ask

How should I store moisture-sensitive bases such as DBU?
Keep the container tightly closed under dry nitrogen or argon, and reseal promptly after each use. DBU and similar bases pick up water and carbon dioxide from air, which reduces their effective strength. For critical reactions, transfer aliquots by syringe through a septum rather than opening the bottle repeatedly.
What does loading mean for a polymer-supported reagent?
Loading is the amount of reactive groups per gram of resin, given in mmol/g. It tells you how much resin to weigh for a set number of equivalents. A range such as 1.5 to 3.0 mmol/g reflects batch variation, so check the COA value for your lot when calculating stoichiometry.
Which derivatisation reagents suit GC analysis of polar compounds?
Silylating, acylating and alkylating agents convert polar groups such as hydroxyls, amines and acids into volatile, thermally stable derivatives. The choice depends on the functional group and detector. Search the catalogue by reagent name or CAS number, or ask us which listed reagents fit your analyte class.

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