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Pharmacopeial Impurities (EP / USP / BP)

Methotrexate EP Impurity C

Reference StandardAvailable on request

Order Methotrexate EP Impurity C (CAS 2410-93-7) online at Zemixal. Lab and bulk packs, batch COA, fast global delivery.

Pack sizes
Methotrexate EP Impurity C chemical structure
CAS number2410-93-7
FormulaC20H21N7O6
Molar mass455.4 g/mol
Physical formSolid
HS code38229090
InChIKeyHLIXOCXUWGDBNP-ZDUSSCGKSA-N
IUPAC name(2S)-2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid

About Methotrexate EP Impurity C

Methotrexate EP Impurity C is supplied by Zemixal as a characterised reference material for Methotrexate analysis. Identity at a glance (Reference Standard): CAS 2410-93-7, formula C20H21N7O6 and molar mass 455.4 g/mol. It is handled as a solid.

Common uses in the lab and plant

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Safe handling

Hazard communication follows GHS (Danger: H301, H302, H315 and H319). Our SDS lists exposure controls and first-aid measures.

Available as 10 mg, 25 mg, 50 mg and 100 mg. Larger or split packs can be arranged. Each lot travels with a certificate of analysis with characterisation data. Send an enquiry through the quote panel and you get a formal offer with Incoterms and delivery time.

Reference standards for Methotrexate

See every impurity, metabolite and related compound we list for this API.

Methotrexate standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Pharmaceutical Manufacturing and QCResearch Labs and Universities

Grade guides

Ph. Eur. Grade (European Pharmacopoeia)

Specifications and identifiers

Specifications of Methotrexate EP Impurity C
Product nameMethotrexate EP Impurity C
Catalogue numberZX-022115
CAS number2410-93-7
IUPAC name(2S)-2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid
Molecular formulaC20H21N7O6
Molar mass455.4 g/mol
Exact mass455.1553
GradeReference Standard
Physical formSolid
XLogP3-0.9
H-bond donors / acceptors5 / 10
Topological polar surface area200 Ų
HS code38229090
InChIKeyHLIXOCXUWGDBNP-ZDUSSCGKSA-N
SMILESCN(CC1=CN=C2C(=N1)C(=O)NC(=N2)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID135434845
SynonymsMethotrexate - Impurity C, Methopterin, Methopterine, N10-Methylfolic acid, 10-Methylfolic acid, 10-Methylpteroylglutamic acid, N10-Methylpteroylglutamic acid, N-(p-(((2-Amino-4-hydroxy-6-pteridyl)methyl)methylamino)benzoyl)glutamic acid, Glutamic acid, N-(p-(((2-amino-4-hydroxy-6-pteridyl)methyl)methylamino)benzoyl)-, N(10)-Methylfolate, 2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

GHS06 Acute toxicity
Acute toxicity
GHS07 Irritant or harmful
Irritant or harmful
GHS08 Health hazard
Health hazard

Signal word Danger

  • H301Toxic if swallowed
  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H341Suspected of causing genetic defects
  • H351Suspected of causing cancer
  • H360May damage fertility or the unborn child
  • H361Suspected of damaging fertility or the unborn child

Precautionary statements P203, P264, P264 + P265, P270, P280, P301 + P316, P301 + P317, P302 + P352, P305 + P351 + P338, P318, P321, P330, P332 + P317, P337 + P317, P362 + P364, P405, P501

Classification summarised from public GHS notifications. It can vary with grade and concentration, so always follow the SDS supplied with your lot.

Pack sizes

Pack sizes of Methotrexate EP Impurity C
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Methotrexate EP Impurity C

Which CAS number identifies Methotrexate EP Impurity C?
Methotrexate EP Impurity C is registered under CAS 2410-93-7. You may also see it listed as Methotrexate - Impurity C, Methopterin, Methopterine. Our catalogue number for this item is ZX-022115.
What are the formula and molar mass of Methotrexate EP Impurity C?
For Methotrexate EP Impurity C, its formula is C20H21N7O6 and its molar mass is 455.4 g/mol. The systematic (IUPAC) name is (2S)-2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid. InChIKey HLIXOCXUWGDBNP-ZDUSSCGKSA-N lets you match it in any structure database.
How is Methotrexate EP Impurity C used in pharmaceutical QC?
Methotrexate EP Impurity C is a characterised reference material linked to Methotrexate. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Methotrexate EP Impurity C?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Methotrexate EP Impurity C?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Methotrexate EP Impurity C to my country?
Yes. Because Methotrexate EP Impurity C is classed as hazardous, it travels in UN-approved packaging as dangerous goods under IATA or IMDG rules, with the export paperwork your broker needs.

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