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Pharmacopeial Impurities (EP / USP / BP)

Methotrexate EP Impurity D

Reference StandardAvailable on request

Order Methotrexate EP Impurity D (CAS 5623-18-7) online at Zemixal: C15H14N6O3, COA and SDS with every lot, worldwide shipping.

Pack sizes
Methotrexate EP Impurity D chemical structure
CAS number5623-18-7
FormulaC15H14N6O3
Molar mass326.31 g/mol
Physical formSolid
HS code38229090
InChIKeyQHNLFEQJGRZKTK-UHFFFAOYSA-N
IUPAC name4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-methylamino]benzoic acid

About Methotrexate EP Impurity D

Analytical teams working on Methotrexate use Methotrexate EP Impurity D as a qualified comparison standard. Identity at a glance (Reference Standard): CAS 5623-18-7, formula C15H14N6O3 and molar mass 326.31 g/mol. It is handled as a solid.

Use cases we see most often

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and custom quantities are quoted on request. Every shipment includes a certificate of analysis with characterisation data. Add it to your quote list and our team replies with price, lead time and shipping options within one business day.

Reference standards for Methotrexate

See every impurity, metabolite and related compound we list for this API.

Methotrexate standards

Typical uses

  • Pharmacopeial method verification
  • Impurity profiling
  • QC release testing
  • ANDA / DMF filings

Applications

Grade guides

Specifications and identifiers

Specifications of Methotrexate EP Impurity D
Product nameMethotrexate EP Impurity D
Catalogue numberZX-022117
CAS number5623-18-7
IUPAC name4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-methylamino]benzoic acid
Molecular formulaC15H14N6O3
Molar mass326.31 g/mol
Exact mass326.1127
GradeReference Standard
Physical formSolid
XLogP3-0.2
H-bond donors / acceptors3 / 7
Topological polar surface area134 Ų
HS code38229090
InChIKeyQHNLFEQJGRZKTK-UHFFFAOYSA-N
SMILESCN(CC1=CN=C2C(=N1)C(=O)NC(=N2)N)C3=CC=C(C=C3)C(=O)O
PubChem CID135441780
SynonymsMethotrexate EP Impurity D (Free Base), Methotrexate - Impurity D, Metfol-B, N10-Methylpteroic acid, N(10)-Methylpteroic acid, n(10)-Methyl pteroic acid, p-((N-(2-Amino-4-hydroxy)pteridin-6-ylmethyl)-N-methylamino)benzoic acid, Benzoic acid, p-(((2-amino-4-hydroxy-6-pteridinyl)methyl)methylamino)-, Benzoic acid, 4-(((2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)methylamino)-, BENZOIC ACID, p-((N-(2-AMINO-4-HYDROXY)PTERIDIN-6-YLMETHYL)-N-METHYLAMINO)-, Benzoic acid, p-[[(2-amino-4-hydroxy-6-pteridinyl)methyl]methylamino]-, Benzoic acid, p-[[N-(2-amino-4-hydroxy)pteridin-6-ylmethyl]-N-methylamino]-

Lot values are stated on the batch certificate of analysis. Ask for a typical COA with your quotation.

Safety and GHS hazards

No GHS classification is on file for this item. Handle it as an unknown laboratory chemical and request the SDS with your quotation.

Pack sizes

Pack sizes of Methotrexate EP Impurity D
10 mgQuoted on request
25 mgQuoted on request
50 mgQuoted on request
100 mgQuoted on request

Need a different size? Bulk drums and custom packing are quoted on request through the quote form on this page.

Questions about Methotrexate EP Impurity D

Which CAS number identifies Methotrexate EP Impurity D?
Methotrexate EP Impurity D is registered under CAS 5623-18-7. You may also see it listed as Methotrexate EP Impurity D (Free Base), Methotrexate - Impurity D, Metfol-B. Our catalogue number for this item is ZX-022117.
What are the formula and molar mass of Methotrexate EP Impurity D?
For Methotrexate EP Impurity D, its formula is C15H14N6O3 and its molar mass is 326.31 g/mol. The systematic (IUPAC) name is 4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-methylamino]benzoic acid. InChIKey QHNLFEQJGRZKTK-UHFFFAOYSA-N lets you match it in any structure database.
How is Methotrexate EP Impurity D used in pharmaceutical QC?
Methotrexate EP Impurity D is a characterised reference material linked to Methotrexate. Laboratories use it to identify and quantify this impurity during method development and validation, stability work, batch release testing and regulatory submissions.
What grade and pack sizes are available for Methotrexate EP Impurity D?
This listing is Reference Standard grade. Standard packs are 10 mg, 25 mg, 50 mg, 100 mg. Larger quantities and custom packing can be quoted on request.
Which documents come with Methotrexate EP Impurity D?
Each lot ships with a batch certificate of analysis and a 16-section GHS safety data sheet. A typical COA or specification sheet can be shared with the quotation before you order.
Can Zemixal ship Methotrexate EP Impurity D to my country?
Yes. Methotrexate EP Impurity D ships worldwide by express courier, air cargo or sea freight, quoted on the Incoterm you prefer, with full export documents.

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