Why do I see ghost peaks with a new bottle of solvent?

Ghost peaks usually come from trace organics that concentrate on the column during equilibration and elute during the gradient. Switching to a gradient-tested HPLC grade, keeping bottles capped and avoiding plastic transfer lines normally removes them.

Does HPLC grade water exist?

Yes. HPLC grade water is specified for low TOC, low UV absorbance and low residue. Many laboratories produce their own with a purification system, but bottled water is useful for validation work or when the system is down.

How long does an opened bottle of HPLC acetonitrile stay usable?

There is no fixed rule, but once opened, solvents absorb water and airborne contaminants. Most laboratories set an in-use period of a few weeks to a few months based on their own baseline checks, and always keep the cap closed.

Chemical grade

HPLC Grade chemicals

Chromatography solvents purified and tested for low UV absorbance, low residue, low water and freedom from particles.

387 products in this grade

HPLC Grade products

385–387 of 387 products

Water, gradient grade chromatography, for HPLC

CAS: 7732-18-5
Formula: H₂O
MW: 18.02 g/mol

ZX-001757

Zeaxanthin 1% (HPLC)

CAS: 144-68-3
Formula: C₄₀H₅₆O₂
MW: 568.9 g/mol

ZX-003902

β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate ≥95% (HPLC)

CAS: 2646-71-1
Formula: C₂₁H₂₆N₇Na₄O₁₇P₃
MW: 833.3 g/mol

ZX-002723

Compare with other grades

GC Grade AR Grade (Analytical Reagent)ACS Grade LR Grade (Laboratory Reagent)Extra Pure Grade Molecular Biology Grade Spectroscopy Grade LC-MS Grade IP Grade (Indian Pharmacopoeia)BP Grade (British Pharmacopoeia)USP Grade (United States Pharmacopeia)Ph. Eur. Grade (European Pharmacopoeia)Food Grade (FCC)Technical Grade Electronic Grade Deuterated and Stable-Isotope-Labelled Compounds Pharmaceutical Secondary Reference Standards Grades guide

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