Can I use a spectroscopy grade solvent for HPLC?

Often the UV performance is similar, but spectroscopy grades are not always filtered to 0.2 µm or tested for residue and gradient behaviour. For HPLC, a purpose-made HPLC grade is the safer choice.

Why does potassium bromide need its own grade?

KBr discs for IR must be transparent across the mid-IR range and free of water, which absorbs strongly. Spectroscopy grade KBr is dried and tested for clear background, and it should be stored in a desiccator.

What causes fluorescence background in a solvent?

Traces of aromatic compounds and some stabilisers fluoresce under UV excitation. Fluorescence grade solvents are purified to remove them, and the COA reports background against a quinine sulfate reference.

Chemical grade

Spectroscopy Grade chemicals

Solvents and salts with guaranteed transmittance in the UV, visible or IR region and low fluorescence, for spectrophotometric work.

155 products in this grade

Spectroscopy Grade products

73–96 of 155 products

Ethanol, for spectroscopy ≥99.8%

CAS: 64-17-5
Formula: C₂H₆O
MW: 46.07 g/mol

ZX-018788

Ethyl acetate, for HPLC, for spectroscopy ≥99.8%

CAS: 141-78-6
Formula: C₄H₈O₂
MW: 88.11 g/mol

ZX-036995

Ethyl acetate, for spectroscopy, 99%+

CAS: 141-78-6
Formula: C₄H₈O₂
MW: 88.11 g/mol

ZX-001863

Ethyl methyl ketone, for HPLC, for spectroscopy ≥99.50%

CAS: 78-93-3
Formula: C₄H₈O
MW: 72.11 g/mol

ZX-037221

Ethylene glycol, spectroscopy grade, ≥99%

CAS: 107-21-1
Formula: C₂H₆O₂
MW: 62.07 g/mol

ZX-001864

Ferric acetylacetonate, for spectroscopy >98%

CAS: 14024-18-1
Formula: C₁₅H₂₁FeO₆
MW: 353.17 g/mol

ZX-037344

Ferrozine (for spectrophotometric determination of iron), for spectroscopy

CAS: 69898-45-9
Formula: C₂₀H₁₃N₄NaO₆S₂
MW: 492.5 g/mol

ZX-019674

Formamide, for UV spectroscopy

CAS: 75-12-7
Formula: CH₃NO
MW: 45.04 g/mol

ZX-001866

Fused silica substrates, 25 mm dia, 1 mm thick

ZX-017069

Fused silica wafers dia 100 mm thick 0.25 mm

ZX-017071

Fused silica wafers dia 100 mm thick 0.5 mm

ZX-017072

Fused silica wafers dia 100 mm thick 1 mm

ZX-017073

Fused silica window, 150 mm dia, 15 mm thick

ZX-017074

Hexadecane, for spectroscopy

CAS: 544-76-3
Formula: C₁₆H₃₄
MW: 226.44 g/mol

ZX-037441

Hexafluoroisopropanol, for spectroscopy, 99.5%

CAS: 920-66-1
Formula: C₃H₂F₆O
MW: 168.04 g/mol

ZX-009110

Hexane, fraction, for HPLC, for spectroscopy 95%

CAS: 110-54-3
Formula: C₆H₁₄
MW: 86.18 g/mol

ZX-037032

Hydrocortisone, LR, for spectroscopy

CAS: 50-23-7
Formula: C₂₁H₃₀O₅
MW: 362.5 g/mol

ZX-038352

Hypoxanthine, for spectroscopy ≥99.00%

CAS: 68-94-0
Formula: C₅H₄N₄O
MW: 136.11 g/mol

ZX-038344

Inosine-5'-monophosphate disodium salt dihydrate, for spectroscopy ≥99.00%

CAS: 4691-65-0
Formula: C₁₀H₁₁N₄Na₂O₈P
MW: 392.17 g/mol

ZX-019573

Ion Exchange Resin 20-50 mesh, for spectroscopy, for molecular biology

CAS: 9002-23-7

ZX-038411

Ion Exchange Resin 20-50 Mesh, for spectroscopy, for molecular biology

CAS: 9002-24-8
Formula: C₁₉₀H₁₇₈N₂₂OS₃
MW: 2882 g/mol

ZX-038412

Ion Exchange Resin 20-50 mesh, LR, for spectroscopy

CAS: 9002-23-7

ZX-038554

Iridium trichloride, for spectroscopy 46%

CAS: 10025-83-9
Formula: Cl₃Ir
MW: 298.57 g/mol

ZX-037181

Isooctane, for HPLC, for spectroscopy 99.5%

CAS: 540-84-1
Formula: C₈H₁₈
MW: 114.23 g/mol

ZX-037027

Compare with other grades

HPLC Grade GC Grade AR Grade (Analytical Reagent)ACS Grade LR Grade (Laboratory Reagent)Extra Pure Grade Molecular Biology Grade LC-MS Grade IP Grade (Indian Pharmacopoeia)BP Grade (British Pharmacopoeia)USP Grade (United States Pharmacopeia)Ph. Eur. Grade (European Pharmacopoeia)Food Grade (FCC)Technical Grade Electronic Grade Deuterated and Stable-Isotope-Labelled Compounds Pharmaceutical Secondary Reference Standards Grades guide

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