Why do I see ghost peaks with a new bottle of solvent?

Ghost peaks usually come from trace organics that concentrate on the column during equilibration and elute during the gradient. Switching to a gradient-tested HPLC grade, keeping bottles capped and avoiding plastic transfer lines normally removes them.

Does HPLC grade water exist?

Yes. HPLC grade water is specified for low TOC, low UV absorbance and low residue. Many laboratories produce their own with a purification system, but bottled water is useful for validation work or when the system is down.

How long does an opened bottle of HPLC acetonitrile stay usable?

There is no fixed rule, but once opened, solvents absorb water and airborne contaminants. Most laboratories set an in-use period of a few weeks to a few months based on their own baseline checks, and always keep the cap closed.

Chemical grade

HPLC Grade chemicals

Chromatography solvents purified and tested for low UV absorbance, low residue, low water and freedom from particles.

387 products in this grade

HPLC Grade products

241–264 of 387 products

Hemin, from porcine, (HPLC) ≥97%

CAS: 16009-13-5
Formula: C₃₄H₃₂ClFeN₄O₄
MW: 651.9 g/mol

ZX-002643

Hexane, fraction, for HPLC, for GC 99%

CAS: 110-54-3
Formula: C₆H₁₄
MW: 86.18 g/mol

ZX-037280

Hexane, fraction, for HPLC, for spectroscopy 95%

CAS: 110-54-3
Formula: C₆H₁₄
MW: 86.18 g/mol

ZX-037032

Hydroxychloroquine sulphate ≥98% (HPLC), powder

CAS: 747-36-4
Formula: C₁₈H₂₈ClN₃O₅S
MW: 434 g/mol

ZX-002871

Hygromycin B, from Streptomyces hygroscopicus, plant cell culture tested, ≥60% (HPLC), lyophilized powder

CAS: 31282-04-9
Formula: C₂₀H₃₇N₃O₁₃
MW: 527.5 g/mol

ZX-003735

Hyperoside, ≥97% (HPLC)

CAS: 482-36-0
Formula: C₂₁H₂₀O₁₂
MW: 464.4 g/mol

ZX-011476

Ibudilast, ≥99% (HPLC)

CAS: 50847-11-5
Formula: C₁₄H₁₈N₂O
MW: 230.31 g/mol

ZX-010924

Imperatorin powder, ≥98% (HPLC)

CAS: 482-44-0
Formula: C₁₆H₁₄O₄
MW: 270.28 g/mol

ZX-002882

Inosine 5′-monophosphate disodium salt, hydrate, ≥99% (HPLC)

CAS: 352195-40-5
Formula: C₁₀H₁₃N₄Na₂O₉P
MW: 410.18 g/mol

ZX-011262

Insulin, ≥ 25 USP units/mg (HPLC), powder

CAS: 11070-73-8
Formula: C₂₅₄H₃₇₇N₆₅O₇₅S₆
MW: 5734 g/mol

ZX-011263

iso-Butyl alcohol, for HPLC

CAS: 78-83-1
Formula: C₄H₁₀O
MW: 74.12 g/mol

ZX-037043

Isooctane, for HPLC 99.5%+

CAS: 540-84-1
Formula: C₈H₁₈
MW: 114.23 g/mol

ZX-001734

Isooctane, for HPLC, for spectroscopy 99.5%

CAS: 540-84-1
Formula: C₈H₁₈
MW: 114.23 g/mol

ZX-037027

Isopropanol, for HPLC, 99%+

CAS: 67-63-0
Formula: C₃H₈O
MW: 60.1 g/mol

ZX-001735

Isopropanol, for HPLC, for spectroscopy ≥99.8%

CAS: 67-63-0
Formula: C₃H₈O
MW: 60.1 g/mol

ZX-036996

Isorhamnetin, ≥95% (HPLC)

CAS: 480-19-3
Formula: C₁₆H₁₂O₇
MW: 316.26 g/mol

ZX-000603

L-Aspartic acid di-tert-butyl ester hydrochloride, ≥98% (HPLC)

CAS: 1791-13-5
Formula: C₁₂H₂₄ClNO₄
MW: 281.77 g/mol

ZX-002123

Lafutidine, ≥98% (HPLC)

CAS: 118288-08-7
Formula: C₂₂H₂₉N₃O₄S
MW: 431.6 g/mol

ZX-010927

Leupeptin, ≥95% (HPLC)

CAS: 103476-89-7
Formula: C₄₀H₇₈N₁₂O₁₂S
MW: 951.2 g/mol

ZX-002654

Levofloxacin, ≥98%(HPLC)

CAS: 100986-85-4
Formula: C₁₈H₂₀FN₃O₄
MW: 361.4 g/mol

ZX-011161

Liproxstatin-1, 98% (HPLC)

CAS: 950455-15-9
Formula: C₁₉H₂₁ClN₄
MW: 340.8 g/mol

ZX-011575

LY-294,002 hydrochloride, ≥98% (HPLC)

CAS: 934389-88-5
Formula: C₁₉H₁₈ClNO₃
MW: 343.8 g/mol

ZX-002896

Marfey's reagent, for HPLC >99%

CAS: 95713-52-3
Formula: C₉H₉FN₄O₅
MW: 272.19 g/mol

ZX-038416

Methane sulphonic acid sodium salt, AR, for HPLC 98%

CAS: 2386-57-4
Formula: CH₃NaO₃S
MW: 118.09 g/mol

ZX-037093

Compare with other grades

GC Grade AR Grade (Analytical Reagent)ACS Grade LR Grade (Laboratory Reagent)Extra Pure Grade Molecular Biology Grade Spectroscopy Grade LC-MS Grade IP Grade (Indian Pharmacopoeia)BP Grade (British Pharmacopoeia)USP Grade (United States Pharmacopeia)Ph. Eur. Grade (European Pharmacopoeia)Food Grade (FCC)Technical Grade Electronic Grade Deuterated and Stable-Isotope-Labelled Compounds Pharmaceutical Secondary Reference Standards Grades guide

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