Why do I see ghost peaks with a new bottle of solvent?

Ghost peaks usually come from trace organics that concentrate on the column during equilibration and elute during the gradient. Switching to a gradient-tested HPLC grade, keeping bottles capped and avoiding plastic transfer lines normally removes them.

Does HPLC grade water exist?

Yes. HPLC grade water is specified for low TOC, low UV absorbance and low residue. Many laboratories produce their own with a purification system, but bottled water is useful for validation work or when the system is down.

How long does an opened bottle of HPLC acetonitrile stay usable?

There is no fixed rule, but once opened, solvents absorb water and airborne contaminants. Most laboratories set an in-use period of a few weeks to a few months based on their own baseline checks, and always keep the cap closed.

Chemical grade

HPLC Grade chemicals

Chromatography solvents purified and tested for low UV absorbance, low residue, low water and freedom from particles.

387 products in this grade

HPLC Grade products

289–312 of 387 products

N,N-Dimethyl formamide, for HPLC, ≥99.9%

CAS: 68-12-2
Formula: C₃H₇NO
MW: 73.09 g/mol

ZX-001739

N,N-Dimethylacetamide, for HPLC, 99%+

CAS: 127-19-5
Formula: C₄H₉NO
MW: 87.12 g/mol

ZX-001740

N,N-Dimethylacetamide, for HPLC, for spectroscopy ≥99.7%

CAS: 127-19-5
Formula: C₄H₉NO
MW: 87.12 g/mol

ZX-038495

N,N-Dimethylformamide, for HPLC, 99%+

CAS: 68-12-2
Formula: C₃H₇NO
MW: 73.09 g/mol

ZX-001741

N,N,N'N'-Tetramethylbenzidine, ≥95% (HPLC)

CAS: 366-29-0
Formula: C₁₆H₂₀N₂
MW: 240.34 g/mol

ZX-002665

Nicorandil, ≥98% (HPLC)

CAS: 65141-46-0
Formula: C₈H₉N₃O₄
MW: 211.17 g/mol

ZX-010936

Nonane sulphonic acid sodium salt, AR, for HPLC

CAS: 35192-74-6
Formula: C₉H₁₉NaO₃S
MW: 230.3 g/mol

ZX-037148

Nonane sulphonic acid sodium salt, for HPLC 98%

CAS: 35192-74-6
Formula: C₉H₁₉NaO₃S
MW: 230.3 g/mol

ZX-000765

NQDI-1, ≥98% (HPLC)

CAS: 175026-96-7
Formula: C₁₉H₁₃NO₄
MW: 319.3 g/mol

ZX-002913

Okadaic acid potassium salt, from Prorocentrum concavum, ≥90% (HPLC), powder

CAS: 155751-72-7
Formula: C₄₄H₆₇KO₁₃
MW: 843.1 g/mol

ZX-007617

Orthophosphoric acid, for HPLC, 85%+

CAS: 7664-38-2
Formula: H₃O₄P
MW: 98 g/mol

ZX-001745

Oxythiamine chloride hydrochloride, ≥95% (HPLC)

CAS: 614-05-1
Formula: C₁₂H₁₇Cl₂N₃O₂S
MW: 338.3 g/mol

ZX-011048

p-Coumaric acid, ≥98% (HPLC)

CAS: 501-98-4
Formula: C₉H₈O₃
MW: 164.16 g/mol

ZX-002921

p-Nitrophenol, for HPLC >99.5%

CAS: 100-02-7
Formula: C₆H₅NO₃
MW: 139.11 g/mol

ZX-037320

p-Xylene, for HPLC 99%

CAS: 106-42-3
Formula: C₈H₁₀
MW: 106.16 g/mol

ZX-037253

Paclitaxel from Taxus brevifolia ≥95% (HPLC), powder

CAS: 33069-62-4
Formula: C₄₇H₅₁NO₁₄
MW: 853.9 g/mol

ZX-002923

PD-407824, ≥98% (HPLC)

CAS: 622864-54-4
Formula: C₂₀H₁₂N₂O₃
MW: 328.3 g/mol

ZX-002926

Pentane, for HPLC 99%+

CAS: 109-66-0
Formula: C₅H₁₂
MW: 72.15 g/mol

ZX-001746

Pentane, for HPLC, for spectroscopy ≥99.0%

CAS: 109-66-0
Formula: C₅H₁₂
MW: 72.15 g/mol

ZX-036998

Perchloric Acid, for HPLC 70%

CAS: 7601-90-3
Formula: ClHO₄
MW: 100.46 g/mol

ZX-037275

Petroleum ether 40-60 °C for HPLC & Spectroscopy

CAS: 8032-32-4
MW: 82.2 g/mol

ZX-001747

Phenylmethanesulphonyl fluoride, 99% (HPLC)

CAS: 329-98-6
Formula: C₇H₇FO₂S
MW: 174.19 g/mol

ZX-002692

Phosphoramidon disodium salt, ≥97% (HPLC)

CAS: 119942-99-3
Formula: C₂₃H₃₂N₃Na₂O₁₀P
MW: 587.5 g/mol

ZX-002696

Pifithrin-μ, ≥97% (HPLC)

CAS: 64984-31-2
Formula: C₈H₇NO₂S
MW: 181.21 g/mol

ZX-010005

Compare with other grades

GC Grade AR Grade (Analytical Reagent)ACS Grade LR Grade (Laboratory Reagent)Extra Pure Grade Molecular Biology Grade Spectroscopy Grade LC-MS Grade IP Grade (Indian Pharmacopoeia)BP Grade (British Pharmacopoeia)USP Grade (United States Pharmacopeia)Ph. Eur. Grade (European Pharmacopoeia)Food Grade (FCC)Technical Grade Electronic Grade Deuterated and Stable-Isotope-Labelled Compounds Pharmaceutical Secondary Reference Standards Grades guide

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