Why do I see ghost peaks with a new bottle of solvent?

Ghost peaks usually come from trace organics that concentrate on the column during equilibration and elute during the gradient. Switching to a gradient-tested HPLC grade, keeping bottles capped and avoiding plastic transfer lines normally removes them.

Does HPLC grade water exist?

Yes. HPLC grade water is specified for low TOC, low UV absorbance and low residue. Many laboratories produce their own with a purification system, but bottled water is useful for validation work or when the system is down.

How long does an opened bottle of HPLC acetonitrile stay usable?

There is no fixed rule, but once opened, solvents absorb water and airborne contaminants. Most laboratories set an in-use period of a few weeks to a few months based on their own baseline checks, and always keep the cap closed.

Chemical grade

HPLC Grade chemicals

Chromatography solvents purified and tested for low UV absorbance, low residue, low water and freedom from particles.

387 products in this grade

HPLC Grade products

313–336 of 387 products

Polyamide, for chromatography

CAS: 63428-83-1

ZX-017969

Polydatin, ≥95% (HPLC)

CAS: 65914-17-2
Formula: C₂₀H₂₂O₈
MW: 390.4 g/mol

ZX-003870

Potassium hydrogen phthalate, for HPLC 99%+

CAS: 877-24-7
Formula: C₈H₅KO₄
MW: 204.22 g/mol

ZX-003105

Potassium phosphate, dibasic, for HPLC, 99%+

CAS: 7758-11-4
Formula: HK₂O₄P
MW: 174.18 g/mol

ZX-003107

Potassium phosphate, dibasic, for HPLC, for spectroscopy

CAS: 7758-11-4
Formula: HK₂O₄P
MW: 174.18 g/mol

ZX-038031

Potassium phosphate, monobasic, for HPLC, 99.5%

CAS: 7778-77-0
Formula: H₂KO₄P
MW: 136.09 g/mol

ZX-003110

Propane sulphonic acid sodium salt, AR, for HPLC

CAS: 14533-63-2
Formula: C₃H₇NaO₃S
MW: 146.14 g/mol

ZX-038128

Propane sulphonic acid sodium salt, for HPLC 99%+

CAS: 14533-63-2
Formula: C₃H₇NaO₃S
MW: 146.14 g/mol

ZX-000766

Propylene carbonate, for HPLC, 99.7%

CAS: 108-32-7
Formula: C₄H₆O₃
MW: 102.09 g/mol

ZX-001748

Pyridine, for HPLC 99%+

CAS: 110-86-1
Formula: C₅H₅N
MW: 79.1 g/mol

ZX-001749

Pyridine, for HPLC, for spectroscopy 99.5%

CAS: 110-86-1
Formula: C₅H₅N
MW: 79.1 g/mol

ZX-037034

Quercetin 3-β-D-glucoside, ≥90% (HPLC)

CAS: 482-35-9
Formula: C₂₁H₂₀O₁₂
MW: 464.4 g/mol

ZX-011484

Quinalizarin, ≥95% (HPLC)

CAS: 81-61-8
Formula: C₁₄H₈O₆
MW: 272.21 g/mol

ZX-002953

Rapamycin, ≥98% (HPLC)

CAS: 53123-88-9
Formula: C₅₁H₇₉NO₁₃
MW: 914.2 g/mol

ZX-003750

Retigabine, ≥98% (HPLC)

CAS: 150812-12-7
Formula: C₁₆H₁₈FN₃O₂
MW: 303.33 g/mol

ZX-002959

Rhodamine B, ≥95% (HPLC)

CAS: 81-88-9
Formula: C₂₈H₃₁ClN₂O₃
MW: 479 g/mol

ZX-000702

Rifapentine, ≥98% (HPLC)

CAS: 61379-65-5
Formula: C₄₇H₆₄N₄O₁₂
MW: 877 g/mol

ZX-011592

Sanguinarine chloride, hydrate, ≥98% (HPLC)

CAS: 5578-73-4
Formula: C₂₀H₁₄ClNO₄
MW: 367.8 g/mol

ZX-002967

SB 203580, ≥98% (HPLC)

CAS: 152121-47-6
Formula: C₂₁H₁₆FN₃OS
MW: 377.4 g/mol

ZX-002968

SB 431542 hydrate ≥98% (HPLC), powder

CAS: 301836-41-9
Formula: C₂₂H₁₆N₄O₃
MW: 384.4 g/mol

ZX-002969

Silibinin, ≥98% (HPLC)

CAS: 22888-70-6
Formula: C₂₅H₂₂O₁₀
MW: 482.4 g/mol

ZX-003881

Simvastatin, ≥97% (HPLC)

CAS: 79902-63-9
Formula: C₂₅H₃₈O₅
MW: 418.6 g/mol

ZX-007998

Sodium acetate anhydrous, for HPLC, for spectroscopy

CAS: 127-09-3
Formula: C₂H₃NaO₂
MW: 82.03 g/mol

ZX-038016

Sodium acetate, anhydrous, for HPLC, 99%

CAS: 127-09-3
Formula: C₂H₃NaO₂
MW: 82.03 g/mol

ZX-003116

Compare with other grades

GC Grade AR Grade (Analytical Reagent)ACS Grade LR Grade (Laboratory Reagent)Extra Pure Grade Molecular Biology Grade Spectroscopy Grade LC-MS Grade IP Grade (Indian Pharmacopoeia)BP Grade (British Pharmacopoeia)USP Grade (United States Pharmacopeia)Ph. Eur. Grade (European Pharmacopoeia)Food Grade (FCC)Technical Grade Electronic Grade Deuterated and Stable-Isotope-Labelled Compounds Pharmaceutical Secondary Reference Standards Grades guide

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